Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 6/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | AHR | P35869 | 3/20 | 0.41 |
| ▸ | HTR3A | P46098 | 3/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5513632 | 0.84 | FAAH (0.49) | ALDH1A1KMT2AESR1ESR2HSP90AA1 | |
| SCHEMBL29793168 | 0.84 | FAAH (0.49) | ALDH1A1KMT2AESR1ESR2HSP90AA1 | |
| SCHEMBL1839676 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KMT2AESR1ESR2HSP90AA1 | |
| SCHEMBL2137945 | 0.79 | ESR1 (0.61) | ALDH1A1ESR1ESR2HSP90AA1MAPT | |
| SCHEMBL5514251 | 0.76 | ACHE (0.41) | ESR1ESR2HSP90AA1HTR3ACHRNA7 | |
| SCHEMBL8290795 | 0.76 | ESR1 (0.41) | ESR1ESR2HSP90AA1 | |
| SCHEMBL5512412 | 0.76 | ESR1 (0.42) | ALDH1A1ESR1ESR2HSP90AA1 | |
| SCHEMBL1101176 | 0.76 | ESR1 (0.45) | ESR1ESR2HSP90AA1HTR3ACHRNA7 | |
| SCHEMBL482377 | 0.76 | IDO1 (0.47) | ALDH1A1KMT2AAHRHTR3ACHRNA7 | |
| SCHEMBL10222158 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KMT2AAHRHTR3ACHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12517144-B2 | Screening method for blood IgA production inhibitor or for prophylactic or therapeutic agent against diseases caused by excessive IgA in blood | SASABE Jumpei (JP) | 2026-01-06 | — | — | US | disclosed |
| CN-112773798-B | Use of known compounds as D-amino acid oxidase inhibitors | 宇凤·简·曾 | 2024-03-29 | — | — | CN | disclosed |
| EP-3498275-B1 | USE OF KNOWN COMPOUNDS AS D-AMINO ACID OXIDASE INHIBITORS | UNIV NAT TAIWAN (TW) | 2023-06-07 | — | — | EP | disclosed |
| US-RE49340-E1 | Use of known compounds as D-amino acid oxidase inhibitors | Tseng, Yufeng Jane (US) | 2022-12-20 | — | — | US | disclosed |
| CN-112773798-A | Use of known compounds as D-amino acid oxidase inhibitors | 宇凤·简·曾 | 2021-05-11 | — | — | CN | disclosed |
| CN-106687626-B | Use of known compounds as D-amino acid oxidase inhibitors | 宇凤·简·曾 | 2021-01-26 | — | — | CN | disclosed |
| US-20200386776-A1 | SCREENING METHOD FOR BLOOD IgA PRODUCTION INHIBITOR OR FOR PROPHYLACTIC OR THERAPEUTIC AGENT AGAINST DISEASES CAUSED BY EXCESSIVE IgA IN BLOOD | SASABE Jumpei (JP) | 2020-12-10 | — | — | US | disclosed |
| EP-3498275-A1 | USE OF KNOWN COMPOUNDS AS D-AMINO ACID OXIDASE INHIBITORS | National Taiwan University (TW) | 2019-06-19 | — | — | EP | disclosed |
| US-9868975-B2 | Use of known compounds as D-amino acid oxidase inhibitors | Tseng, Yufeng Jane (US) | 2018-01-16 | — | — | US | disclosed |
| EP-3137658-A1 | USE OF KNOWN COMPOUNDS AS D-AMINO ACID OXIDASE INHIBITORS | Tseng, Yufeng, Jane (US) | 2017-03-08 | — | — | EP | disclosed |
| CN-1055686-C | Substituted Benzisoxazole and benzisothiazole herbicidal agents | AMERICAN CYANAMID CO (US) | 2000-08-23 | — | — | CN | disclosed |
| US-6096771-A | ISOXAZOLE DERIVATIVES EXHIBITING EXCELLENT TYPE B AND TYPE A MONOAMINE OXIDASE INHIBITORY ACTIVITIES, THEREFORE USEFUL FOR PREVENTING PARKINSON'S DISEASE, DEPRESSION AND ALZHEIMER'S DISEASE | SANKYO COMPANY, LIMITED (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5965591-A | MONOAMINE OXIDASE INHIBITOR; FOR PROPHYLAXIS AND TREATING PARKINSON'S DISEASE, DEPRESSION AND ALZHEIMER'S DISEASE | SANKYO COMPANY, LIMITED (JP) | 1999-10-12 | — | — | US | disclosed |
| CN-1162957-A | Isoxazole derivatives | SANKYO CO (JP) | 1997-10-22 | — | — | CN | disclosed |
| EP-0779281-A1 | ISOXAZOLES | SANKYO COMPANY LIMITED (JP) | 1997-06-18 | — | — | EP | disclosed |
| CN-1136561-A | Substituted Benzisoxazole and benzisothiazole herbicidal agents | AMERICAN CYANAMID CO (US) | 1996-11-27 | — | — | CN | disclosed |
| EP-0726268-A1 | Substituted benzisoxazole and benzisothiazole herbicidal agents | American Cyanamid Company (US) | 1996-08-14 | — | — | EP | disclosed |
| US-5523278-A | PRE- AND POST-EMERGENCE HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1996-06-04 | — | — | US | disclosed |
| US-5484763-A | Substituted benzisoxazole and benzisothiazole herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1996-01-16 | — | — | US | disclosed |
| US-4127653-A | INSECTICIDE, MITICIDE, NEMATOCIDE, FUNGICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-28 | — | — | US | disclosed |