SCHEMBL1454677

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7174301	0.98	GAA (0.46)	GAAEPHX1ALDH1A1HTTCACNA2D1
	SCHEMBL1454049	0.98	GAA (0.46)	GAAEPHX1ALDH1A1HTTCACNA2D1
	SCHEMBL9146997	0.98	GAA (0.46)	GAAEPHX1ALDH1A1HTTCACNA2D1
	SCHEMBL11726260	0.93	MAPT (0.44)	GAAALDH1A1HTTCACNA2D1KCNH3
	SCHEMBL14840338	0.89	SOAT2 (0.52)	GAASOAT2SOAT1MAPT
	SCHEMBL21634339	0.87	MAPT (0.46)	GAAALDH1A1HTTCACNA2D1KCNH3
	SCHEMBL1453847	0.86	GAA (0.43)	GAAALDH1A1CACNA2D1NPSR1ALOX12
	SCHEMBL29769245	0.84	ESR1 (0.36)	GAAHTTCACNA2D1MEN1KMT2A
	SCHEMBL23633882	0.83	GAA (0.46)	GAAEPHX1ALDH1A1HTTKCNH3
	SCHEMBL25857253	0.83	GAA (0.46)	GAAEPHX1ALDH1A1HTTKCNH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.