Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7174301 | 1.00 | GAA (0.46) | GAAEPHX1ALDH1A1HTTCACNA2D1 | |
| SCHEMBL1454049 | 1.00 | GAA (0.46) | GAAEPHX1ALDH1A1HTTCACNA2D1 | |
| SCHEMBL1454677 | 0.98 | GAA (0.47) | GAAEPHX1ALDH1A1HTTCACNA2D1 | |
| SCHEMBL11726260 | 0.91 | MAPT (0.44) | GAAALDH1A1HTTCACNA2D1KCNH3 | |
| SCHEMBL14840338 | 0.91 | SOAT2 (0.52) | GAASOAT2SOAT1 | |
| SCHEMBL21634339 | 0.86 | MAPT (0.46) | GAAALDH1A1HTTCACNA2D1KCNH3 | |
| SCHEMBL23633882 | 0.85 | GAA (0.46) | GAAEPHX1ALDH1A1HTTKCNH3 | |
| SCHEMBL1453847 | 0.84 | GAA (0.43) | GAAALDH1A1CACNA2D1NPSR1 | |
| SCHEMBL11329795 | 0.83 | GAA (0.47) | GAAEPHX1ALDH1A1HTTKCNH3 | |
| SCHEMBL19352986 | 0.82 | NAAA (0.41) | ALDH1A1HTTHDAC3NAAAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457272-A | Method for capturing ecologically harmful substances from material polluted with such substances | PELT & HOOYKAAS B.V. (NL) | 1995-10-10 | — | — | US | disclosed |
| EP-0626346-A1 | Method for capturing ecologically harmful substances from material polluted with such substances | PELT & HOOYKAAS B.V. (NL) | 1994-11-30 | — | — | EP | disclosed |
| EP-0398410-B1 | PROCESS FOR IMMOBILIZING ENVIRONMENTALLY NOXIOUS METALS AND ORGANIC SUBSTANCES | PELT & HOOYKAAS B.V. (NL) | 1993-01-20 | — | — | EP | disclosed |
| US-5028338-A | Process for immobilizing environmentally noxious metals and organic substances | PELT & HOOYKAAS (NL) | 1991-07-02 | — | — | US | disclosed |
| EP-0398410-A1 | Process for immobilizing environmentally noxious metals and organic substances | PELT & HOOYKAAS B.V. (NL) | 1990-11-22 | — | — | EP | disclosed |