Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365794 | 0.85 | ACP3 (0.50) | LMNAALOX5KDM1AALDH1A1KMT2A | |
| SCHEMBL5513822 | 0.85 | ACP3 (0.50) | LMNAALOX5KDM1AALDH1A1KMT2A | |
| SCHEMBL8766752 | 0.84 | LMNA (0.49) | LMNANPSR1CRHBPCRHR2TSHR | |
| SCHEMBL7890911 | 0.84 | LMNA (0.49) | LMNANPSR1CRHBPCRHR2TSHR | |
| SCHEMBL9574986 | 0.84 | LMNA (0.49) | LMNANPSR1CRHBPCRHR2TSHR | |
| Hydrochloric Acid SCHEMBL5967058 | 0.83 | ACP3 (0.53) | LMNAALOX5KDM1AALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL5967292 | 0.83 | ACP3 (0.53) | LMNAALOX5KDM1AALDH1A1KMT2A | |
| SCHEMBL4679414 | 0.83 | KMT2A (0.58) | LMNANPSR1KDM1ACRHBPCRHR2 | |
| SCHEMBL4679411 | 0.83 | KMT2A (0.58) | LMNANPSR1KDM1ACRHBPCRHR2 | |
| SCHEMBL7318693 | 0.81 | LMNA (0.47) | LMNANPSR1ALOX5GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |