SCHEMBL551395

SCHEMBL551395

CCc1ccc(O)c(Cc2c(O)ccc(CC)c2C(C)(C)C)c1C(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.39
ESR2 Q92731 3/20 0.39
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
CYP1A2 P05177 2/20 0.33
HSD17B10 Q99714 2/20 0.33
BACE1 P56817 1/20 0.33
HSPA5 P11021 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TP53 P04637 1/20 0.33
HSP90AA1 P07900 3/20 0.33
HSP90AB1 P08238 3/20 0.33
PRKCI P41743 1/20 0.33
CYP2D6 P10635 1/20 0.33
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TRPA1 O75762 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27515343 0.85 BACE1 (0.39) ESR1ESR2GABRA1GABRB2HSD17B10
SCHEMBL2040206 0.82 GABRA1 (0.43) ESR1ESR2GABRA1GABRB2HSD17B10
SCHEMBL5571089 0.79 GABRA1 (0.43) GABRA1GABRB2ALDH1A1HPGD
SCHEMBL7860016 0.78 TYR (0.41) ESR1ESR2GABRA1GABRB2BACE1
SCHEMBL6323325 0.77 HSPA5 (0.37) ESR1ESR2GABRA1GABRB2HSD17B10
SCHEMBL550887 0.76 ESR1 (0.38) ESR1ESR2GABRA1GABRB2CYP1A2
SCHEMBL1861164 0.73 ESR1 (0.39) ESR1ESR2GABRA1GABRB2HSD17B10
SCHEMBL29429347 0.73 GABRA1 (0.52) ESR1ESR2GABRA1GABRB2BACE1
SCHEMBL3191260 0.73 GABRA1 (0.52) ESR1ESR2GABRA1GABRB2BACE1
SCHEMBL6407131 0.72 GABRA1 (0.58) GABRA1GABRB2HSPA5ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1652891-B1 CURABLE RESIN COMPOSITION AND COLD-SETTING ADHESIVE KONISHI CO LTD (JP) 2012-06-13 EP disclosed
US-8110645-B2 Curable resin composition KONISHI CO., LTD. (JP) 2012-02-07 US disclosed
EP-1788035-B1 REACTIVE HOT-MELT RESIN COMPOSITION AND REACTIVE HOT-MELT ADHESIVE KONISHI CO LTD (JP) 2011-01-19 EP disclosed
EP-1605026-B1 Polymeric dispersants KAO CORP (JP) 2010-04-07 EP disclosed
US-7666924-B2 Water-based ink including an acrylic copolymer based on a monomer of an acidacid phosphoxytri(methylene glyco)(meth)acrylate and a pigment, carbon black;ink-jet printing; excellent storage stability; glossy paper; adhesion KAO CORPORATION (JP) 2010-02-23 US disclosed
US-20090264602-A1 Curable Resin Composition and Cold Setting Adhesive KONISHI CO., LTD. (JP) 2009-10-22 US disclosed
US-7576167-B2 Curable resin composition KONISHI CO., LTD. (JP) 2009-08-18 US disclosed
US-20080312401-A1 Reactive Hot-Melt Resin Composition and Reactive Hot-Melt Adhesive SATO SHINICHI 2008-12-18 US disclosed
US-7449519-B2 Curing resin, method for producing same and curing resin composition KONISHI CO., LTD. (JP) 2008-11-11 US disclosed
EP-1788035-A1 REACTIVE HOT-MELT RESIN COMPOSITION AND REACTIVE HOT-MELT ADHESIVE Konishi Co., Ltd. (JP) 2007-05-23 EP disclosed
EP-1616886-A1 CURING RESIN, METHOD FOR PRODUCING SAME AND CURING RESIN COMPOSITION Konishi Co., Ltd. (JP) 2006-01-18 EP disclosed
US-20050282932-A1 Polymeric dispersants KAO CORPORATION (JP) 2005-12-22 US disclosed
EP-1605026-A1 Polymeric dispersants Kao Corporation (JP) 2005-12-14 EP disclosed
US-6914098-B2 Acrylic elastomer and its composition NIPPON MEKIRON, LIMITED (JP) 2005-07-05 US disclosed
US-6811964-B2 MIXING A SILVER HALIDE PARTICLE FEEDING SOLUTION IN A MOTHER LIQUID OF COATING LIQUID. FUJI PHOTO FILM CO., LTD. (JP) 2004-11-02 US disclosed
WO-2004069949-A1 METHOD OF BONDING ETHYLENE-VINYL ACETATE COPOLYMER FORMED PRODUCT CANON KABUSHIKI KAISHA (JP) 2004-08-19 WO disclosed
US-20040087729-A1 Acrylic elastomer and its composition MORIYAMA IWAO (JP) 2004-05-06 US disclosed
US-20040019154-A1 Acrylic elastomer and its composition MORIYAMA IWAO (JP) 2004-01-29 US disclosed
US-20010005742-A1 Acrylic elastomer and its composition NIPPON MEKTRON, LIMITED 2001-06-28 US disclosed
EP-1110980-A1 Acrylic elastomer and its composition Nippon Mektron, Limited (JP) 2001-06-27 EP disclosed