SCHEMBL7860016

SCHEMBL7860016

CCc1ccc(O)c(C)c1C(C)(C)C

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.41
ESR1 P03372 7/20 0.40
ESR2 Q92731 7/20 0.40
GABRA1 P14867 1/20 0.40
GABRB2 P47870 1/20 0.40
TRPA1 O75762 1/20 0.35
ATM Q13315 1/20 0.35
NR3C1 P04150 2/20 0.35
PGR P06401 2/20 0.35
NR3C2 P08235 2/20 0.35
AR P10275 1/20 0.34
BACE1 P56817 1/20 0.34
PRKCI P41743 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28455890 0.85 TYR (0.46) TYRESR1ESR2TRPA1ATM
SCHEMBL2040206 0.83 GABRA1 (0.43) TYRESR1ESR2GABRA1GABRB2
Butane SCHEMBL27448856 0.79 TYR (0.39) TYRESR1ESR2TRPA1ATM
SCHEMBL28591591 0.79 POLB (0.45) ESR1ESR2
SCHEMBL70108 0.79 TYR (0.60) TYRESR1ESR2GABRA1GABRB2
SCHEMBL551395 0.78 ESR1 (0.39) ESR1ESR2GABRA1GABRB2TRPA1
SCHEMBL4483852 0.78 TRPA1 (0.44) TYRESR1ESR2GABRA1GABRB2
SCHEMBL4888228 0.76 TYR (0.47) TYRESR1ESR2GABRA1GABRB2
SCHEMBL30597484 0.76 TYR (0.47) TYRESR1ESR2GABRA1GABRB2
SCHEMBL27515343 0.76 BACE1 (0.39) ESR1ESR2GABRA1GABRB2BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101624442-A Polycarbonate resin and electrophotographic photoreceptor using the same IDEMITSU KOSAN CO 2010-01-13 CN claimed
CN-116736653-A Electrophotographic photoreceptor, process cartridge, and image forming apparatus 富士胶片商业创新有限公司 2023-09-12 CN disclosed
CN-107844036-B Electrophotographic photoreceptor, process cartridge, and image forming apparatus 富士胶片商业创新有限公司 2022-08-30 CN disclosed
CN-105929642-B Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and method of manufacturing electrophotographic photosensitive member 佳能株式会社 2020-09-01 CN disclosed
CN-105867079-B Electrophotographic photoreceptor, process cartridge, and image forming apparatus 富士施乐株式会社 2019-12-17 CN disclosed
CN-101624442-A Polycarbonate resin and electrophotographic photoreceptor using the same IDEMITSU KOSAN CO 2010-01-13 CN disclosed
CN-100567365-C Polycarbonate resin and electrophotographic photoreceptor using the same IDEMITSU KOSAN CO (JP) 2009-12-09 CN disclosed
CN-1957017-A Polycarbonate resin and electrophotographic photoreceptor using the same IDEMITSU KOSAN CO (JP) 2007-05-02 CN disclosed
EP-1069146-A1 POLYCARBONATE AND OPTICAL MATERIAL Idemitsu Petrochemical Co., Ltd. (JP) 2001-01-17 EP disclosed
EP-1035150-A1 COPOLYCARBONATE AND PROCESS FOR PRODUCING THE SAME IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2000-09-13 EP disclosed