Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5510323 | 0.85 | KDM4E (0.35) | KDM4E | |
| Hydrochloric Acid SCHEMBL5515649 | 0.83 | SLC6A2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL5522403 | 0.80 | HCRTR1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL5515600 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL5515983 | 0.76 | KDM4E (0.32) | KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL5517428 | 0.72 | METAP2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL5517958 | 0.72 | TDP1 (0.33) | KDM4E | |
| SCHEMBL8673527 | 0.70 | CYP2A6 (0.42) | KDM4EALDH1A1CYP2A6HPGDHTT | |
| Hydrochloric Acid SCHEMBL6064180 | 0.68 | CYP2A6 (0.41) | KDM4EALDH1A1CYP2A6NPC1HPGD | |
| Hydrochloric Acid SCHEMBL7734464 | 0.68 | ALDH1A1 (0.39) | KDM4EALDH1A1CYP2A6HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208559-B2 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2007-04-24 | — | — | US | disclosed |
| US-20060135712-A1 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2006-06-22 | — | — | US | disclosed |