Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5948977 | 0.90 | DNM1 (0.38) | DNM1OPRM1ALDH1A1TDP1PLA2G1B | |
| SCHEMBL24693228 | 0.85 | DNM1 (0.35) | DNM1OPRM1ALDH1A1TDP1PLA2G1B | |
| SCHEMBL23105001 | 0.84 | MEN1 (0.32) | TSHR | |
| SCHEMBL20729902 | 0.83 | MEN1 (0.39) | — | |
| SCHEMBL19919864 | 0.83 | DNM1 (0.33) | DNM1OPRM1SPHK1TP53ALDH1A1 | |
| SCHEMBL21558638 | 0.83 | ALDH1A1 (0.34) | DNM1OPRM1ALDH1A1TDP1TSHR | |
| SCHEMBL372737 | 0.82 | OPRM1 (0.46) | DNM1OPRM1SPHK1TP53PLA2G1B | |
| SCHEMBL9949304 | 0.81 | SPHK1 (0.34) | DNM1OPRM1SPHK1ALDH1A1 | |
| SCHEMBL5948699 | 0.80 | OPRM1 (0.44) | DNM1OPRM1SPHK1PLA2G1BPLA2G2A | |
| Hexane SCHEMBL28248500 | 0.78 | TSHR (0.41) | DNM1OPRM1SPHK1TP53PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774817-B1 | BCL6 INHIBITORS | CANCER RESEARCH TECH LTD (GB) | 2022-12-07 | — | — | EP | disclosed |
| EP-1756089-A1 | MERCAPTOIMIDAZOLES AS CCR2 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005118574-A1 | MERCAPTOIMIDAZOLES AS CCR2 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-12-15 | — | — | WO | disclosed |