Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29442601 | 0.80 | MAPT (0.47) | MAPTTP53HSD17B10GAAMAPK1 | |
| SCHEMBL453906 | 0.80 | MAPT (0.47) | MAPTTP53HSD17B10GAAMAPK1 | |
| SCHEMBL5809523 | 0.77 | MAPT (0.47) | MAPTTP53HSD17B10GAAMAPK1 | |
| SCHEMBL3151717 | 0.77 | MAPT (0.67) | MAPTGAAHTTALDH1A1KMT2A | |
| SCHEMBL3879536 | 0.76 | BRD4 (0.46) | MAPTTP53HSD17B10GAAMAPK1 | |
| SCHEMBL3194480 | 0.76 | MAPT (0.50) | MAPTTP53HSD17B10GAAMAPK1 | |
| SCHEMBL7157690 | 0.75 | TP53 (0.38) | MAPTTP53HSD17B10GAAMAPK1 | |
| SCHEMBL456864 | 0.75 | MAPT (0.43) | MAPTTP53HSD17B10GAAMAPK1 | |
| SCHEMBL3879346 | 0.75 | MAPK1 (0.46) | MAPTTP53HSD17B10GAAMAPK1 | |
| SCHEMBL22580936 | 0.71 | TYR (0.37) | MAPTTP53HSD17B10GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846108-A2 | KERATIN DYEING COMPOSITIONS CONTAINING BENZOTHIAZOLE-4,7-DIAMINES, AND USE THEREOF | The Procter & Gamble Company (US) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006078800-A2 | KERATIN DYEING COMPOSITIONS CONTAINING BENZOTHIAZOLE-4-, 7-DIAMINES, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-27 | — | — | WO | disclosed |