Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7157690 | 0.93 | TP53 (0.38) | MAPTTP53GAAHSD17B10MAPK1 | |
| SCHEMBL10601266 | 0.85 | MAPT (0.47) | MAPTTP53GAAHSD17B10MAPK1 | |
| SCHEMBL11839093 | 0.82 | KDM4E (0.48) | MAPTTP53GAAHSD17B10LMNA | |
| SCHEMBL5268912 | 0.81 | ALDH1A1 (0.43) | MAPTTP53GAAHSD17B10MAPK1 | |
| SCHEMBL29039607 | 0.80 | KDM4E (0.36) | MAPTTP53GAAHSD17B10LMNA | |
| SCHEMBL28074764 | 0.77 | LMNA (0.60) | MAPTHSD17B10LMNASMN1; SMN2MEN1 | |
| SCHEMBL453906 | 0.75 | MAPT (0.47) | MAPTTP53GAAHSD17B10MAPK1 | |
| SCHEMBL29442601 | 0.75 | MAPT (0.47) | MAPTTP53GAAHSD17B10MAPK1 | |
| SCHEMBL5514754 | 0.75 | MAPT (0.44) | MAPTTP53GAAHSD17B10MAPK1 | |
| SCHEMBL3194480 | 0.74 | MAPT (0.50) | MAPTTP53GAAHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 942 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4785024-B2 | — | — | 2011-10-05 | — | — | JP | claimed |
| EP-1494995-B1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | PROCTER & GAMBLE (US) | 2010-09-22 | — | — | EP | claimed |
| US-RE41549-E1 | Dyes for keratin fibers, the dyes containing n-benzyl-p-phenylenediamine derivatives and novel n-benzyl-p-phenylenediamine derivatives | WELLA AG (DE) | 2010-08-24 | — | — | US | claimed |
| US-7771734-B2 | Process to color and permanently restructure hair | WELLA AG (DE) | 2010-08-10 | — | — | US | claimed |
| EP-1670423-B1 | DYE-CONTAINING PELLETS FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2008-10-08 | — | — | EP | claimed |
| EP-1655056-B1 | Process to colour and permanently restructure hair | WELLA AG (DE) | 2008-07-02 | — | — | EP | claimed |
| EP-1601335-B1 | MEANS AND METHOD FOR THE SIMULTANEOUS BLEACHING AND DYEING OF KERATIN FIBRES | WELLA AG (DE) | 2008-03-19 | — | — | EP | claimed |
| US-7326254-B2 | Means and method for the simultaneous bleaching and dyeing of keratin fibres | WELLA AG (DE) | 2008-02-05 | — | — | US | claimed |
| EP-1351945-B1 | NOVEL 1,4-DIAMINO-2-(THIAZOL-2-YL)BENZENE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2008-01-23 | — | — | EP | claimed |
| EP-1599178-B1 | MEANS AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2007-12-19 | — | — | EP | claimed |
| US-20010054207-A1 | p-aminophenol derivative compounds and dye compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2001-12-27 | — | — | US | claimed |
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | claimed |
| WO-2001085683-A2 | PYRROLYL-, FURANYL- AND THIENYL-SUBSTITUTED P-AMINOPHENOLS AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2001-11-15 | — | — | WO | claimed |
| EP-1153917-A1 | p-Aminophenol derivatives and colorants containing them | Wella Aktiengesellschaft (DE) | 2001-11-14 | — | — | EP | claimed |
| WO-2001072686-A1 | P-DIAMINOBENZENE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2001-10-04 | — | — | WO | claimed |
| EP-1116711-A2 | 2-aminoalkyl-1,4-diaminobenzene derivatives and dye composition containing these compounds | Wella Aktiengesellschaft (DE) | 2001-07-18 | — | — | EP | claimed |
| US-6132475-A | FOR OXIDATION DYEING OF KERATIN FIBERS; INCLUDES COUPLER AND DEVELOPER, IN WHICH THE DEVELOPER IS A SUBSTITUTED 2-(FURYL, THIENYL, PYRROLYL, OR SELENOPHENE) P-DIAMINOBENZENE DERIVATIVE OF GIVEN FORMULA; COLORFASTNESS, WASHFASTNESS | WELLA AKTIENGESELLSCHAFT (DE) | 2000-10-17 | — | — | US | claimed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | claimed |
| EP-0963982-A2 | New diaminobenzene derivatives and these componends containing colouring agents | Wella Aktiengesellschaft (DE) | 1999-12-15 | — | — | EP | claimed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010054207-A1 | p-aminophenol derivative compounds and dye compositions containing same | KRT18, AASDHPPT, S100P | MAPT 663/4885TP53 304/4885GAA 4705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.