Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 1/20 | 0.51 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 7/20 | 0.47 |
| ▸ | THRA | P10827 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21725512 | 0.82 | NQO1 (0.43) | MAPTL3MBTL1TSHRLMNA | |
| SCHEMBL5543083 | 0.81 | MCL1 (0.56) | AGERPTPN7MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL5514421 | 0.81 | PTPN7 (0.53) | PTPN7THRBTHRAMAPTL3MBTL1 | |
| SCHEMBL17896566 | 0.79 | SMN1; SMN2 (0.55) | AGERPTPN7THRBTHRAMAPT | |
| SCHEMBL25063883 | 0.79 | KMT2A (0.48) | MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL585845 | 0.79 | AGER (0.56) | AGERPTPN7MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL2950207 | 0.79 | MCL1 (0.62) | PTPN7THRBTHRAMAPTL3MBTL1 | |
| SCHEMBL25725072 | 0.78 | SMN1; SMN2 (0.54) | PTPN7THRBTHRAMAPTL3MBTL1 | |
| SCHEMBL24935669 | 0.78 | THRA (0.41) | THRBTHRAPPARDPPARASRD5A2 | |
| SCHEMBL22666573 | 0.78 | THRB (0.61) | AGERPTPN7THRBTHRAMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |