Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 12/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6696457 | 0.84 | CHRM5 (0.43) | SLC6A2CHRM5CHKA | |
| SCHEMBL709443 | 0.80 | TP53 (0.43) | — | |
| SCHEMBL571886 | 0.73 | SLC6A2 (0.49) | SLC6A2CHRM5CHKA | |
| SCHEMBL8281666 | 0.71 | CHRM5 (0.52) | SLC6A2CHRM5CHKA | |
| SCHEMBL1998842 | 0.70 | DRD3 (0.46) | — | |
| SCHEMBL2000378 | 0.70 | RAB9A (0.33) | — | |
| SCHEMBL1995895 | 0.70 | CETP (0.31) | — | |
| SCHEMBL8021770 | 0.69 | SLC6A2 (0.46) | SLC6A2CHRM5CHKA | |
| Hydrochloric Acid SCHEMBL5395464 | 0.69 | CHRM5 (0.50) | SLC6A2CHRM5CHKA | |
| SCHEMBL489807 | 0.69 | TDP1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223755-B2 | Hydroxymorpholinone derivative and medicinal use thereof | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2007-05-29 | — | — | US | disclosed |
| US-20050176704-A1 | Hydroxymorpholinone derivative and medicinal use thereof | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176704-A1 | Hydroxymorpholinone derivative and medicinal use thereof | CAPN1, OPRM1, CAPN2 | SLC6A2 564/4885CHRM5 1025/4885CHKA 3733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.