Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.59 |
| ▸ | DHODH | Q02127 | 1/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.53 |
| ▸ | TYR | P14679 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5513452 | 0.85 | MAPT (0.66) | MAPTMEN1KMT2ALMNAHPGD | |
| SCHEMBL9578201 | 0.81 | CTSL (0.83) | MAPTMEN1KMT2ALMNAHPGD | |
| SCHEMBL31297033 | 0.80 | CTSL (0.64) | MAPTMEN1KMT2ALMNAHPGD | |
| SCHEMBL5517304 | 0.78 | MAPT (0.63) | MAPTMEN1KMT2ALMNASENP8 | |
| SCHEMBL9578101 | 0.78 | CYP19A1 (0.50) | MAPTMEN1KMT2ALMNAHPGD | |
| SCHEMBL5523466 | 0.78 | MAPT (0.60) | MAPTMEN1KMT2ALMNAHPGD | |
| SCHEMBL5513429 | 0.78 | CTSL (0.61) | MAPTMEN1KMT2ALMNASENP8 | |
| SCHEMBL5513553 | 0.77 | MEN1 (0.65) | MAPTMEN1KMT2ALMNAHPGD | |
| Dihydroxanthohumol SCHEMBL15704299 | 0.76 | MAPT (1.00) | MAPTMEN1KMT2ALMNAHPGD | |
| SCHEMBL6819084 | 0.75 | MAPT (0.47) | MAPTMEN1KMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | disclosed |
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | disclosed |
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | disclosed |
| EP-1623704-A1 | THERAPEUTIC AGENT | TAKARA BIO INC. (JP) | 2006-02-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070092551-A1 | Therapeutic agent | FABP4, GPR119, IAPP | MAPT 2256/4885MEN1 2467/4885KMT2A 4418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.