SCHEMBL5515027

SCHEMBL5515027

O=C(O)COC(Nn1cccc1)C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
CTH P32929 1/20 0.31
CBS P35520 1/20 0.31
THPO P40225 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
PTPN7 P35236 1/20 0.31
KMT2A Q03164 1/20 0.31
PTPN12 Q05209 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30768315 0.68 ALDH1A1 (0.49) TSHRMEN1ALDH1A1MAPTPTPN7
SCHEMBL5516799 0.68 CYP2D6 (0.32)
SCHEMBL7522224 0.66 KMT2A (0.43) MEN1MAPTKMT2A
SCHEMBL7274425 0.65 HDAC4 (0.34) TSHRMEN1MAPTKMT2A
SCHEMBL5515039 0.65 HDAC4 (0.34) TSHRMEN1MAPTKMT2A
SCHEMBL5521550 0.62 HDAC1 (0.39) THRB
SCHEMBL6915953 0.60 ALOX15 (0.45) TSHRMEN1ALDH1A1MAPTPTPN7
SCHEMBL5513160 0.60 NPSR1 (0.33) KMT2A
SCHEMBL11340381 0.60 TSHR (0.41) TSHRCTHCBSTHPOMEN1
SCHEMBL170210 0.60 TSHR (0.41) TSHRCTHCBSTHPOTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed