SCHEMBL5515052

SCHEMBL5515052

CC(C)=CCCC(C)=CCc1c(O)ccc(C(=O)C=Cc2ccc(Cl)cc2)c1O

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.84
MEN1 O00255 2/20 0.84
LMNA P02545 2/20 0.84
MAPT P10636 2/20 0.84
KMT2A Q03164 2/20 0.84
ALDH1A1 P00352 1/20 0.84
GAA P10253 1/20 0.84
PTPN1 P18031 2/20 0.67
DHODH Q02127 1/20 0.67
PPARG P37231 3/20 0.61
PPARA Q07869 3/20 0.61
MGAM O43451 1/20 0.61
CASP3 P42574 1/20 0.60
SENP8 Q96LD8 1/20 0.60
SENP7 Q9BQF6 1/20 0.60
SENP6 Q9GZR1 1/20 0.60
PTGS1 P23219 2/20 0.58
PTGS2 P35354 2/20 0.58
CYP19A1 P11511 2/20 0.53
TYR P14679 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5515045 1.00 MAOB (0.84) MAOBMEN1LMNAMAPTKMT2A
SCHEMBL5515048 1.00 MAOB (0.84) MAOBMEN1LMNAMAPTKMT2A
Xanthoangelol SCHEMBL5519362 0.92 MEN1 (1.00) MAOBMEN1LMNAMAPTKMT2A
Xanthoangelol SCHEMBL5519356 0.92 MEN1 (1.00) MAOBMEN1LMNAMAPTKMT2A
Xanthoangelol SCHEMBL454823 0.92 MEN1 (1.00) MAOBMEN1LMNAMAPTKMT2A
SCHEMBL14523853 0.91 MEN1 (0.98) MAOBMEN1LMNAMAPTKMT2A
SCHEMBL5515022 0.91 MEN1 (0.98) MAOBMEN1LMNAMAPTKMT2A
SCHEMBL5518698 0.90 PTPN1 (0.82) MAOBMEN1LMNAMAPTKMT2A
SCHEMBL5518692 0.90 PTPN1 (0.82) MAOBMEN1LMNAMAPTKMT2A
SCHEMBL29435866 0.84 MEN1 (0.74) MAOBMEN1LMNAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070092551-A1 Therapeutic agent TAKARA BIO INC. (JP) 2007-04-26 US claimed
EP-1623704-A1 THERAPEUTIC AGENT TAKARA BIO INC. (JP) 2006-02-08 EP claimed
US-20070092551-A1 Therapeutic agent TAKARA BIO INC. (JP) 2007-04-26 US disclosed
EP-1623704-A1 THERAPEUTIC AGENT TAKARA BIO INC. (JP) 2006-02-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070092551-A1 Therapeutic agent FABP4, GPR119, IAPP MAOB 4382/4885MEN1 2467/4885LMNA 2982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.