Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.82 |
| ▸ | DHODH | Q02127 | 1/20 | 0.82 |
| ▸ | MAOB | P27338 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.63 |
| ▸ | TYR | P14679 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | GUSB | P08236 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5518698 | 1.00 | PTPN1 (0.82) | PTPN1DHODHMAOBMEN1LMNA | |
| SCHEMBL5515045 | 0.90 | MAOB (0.84) | PTPN1DHODHMAOBMEN1LMNA | |
| SCHEMBL5515048 | 0.90 | MAOB (0.84) | PTPN1DHODHMAOBMEN1LMNA | |
| SCHEMBL5515052 | 0.90 | MAOB (0.84) | PTPN1DHODHMAOBMEN1LMNA | |
| Isobavachalcone SCHEMBL600137 | 0.90 | PTPN1 (1.00) | PTPN1DHODHMAOBMEN1LMNA | |
| Isocordoin SCHEMBL24075559 | 0.88 | PTPN1 (0.81) | PTPN1DHODHMAOBMEN1LMNA | |
| SCHEMBL29696899 | 0.86 | PTPN1 (0.82) | PTPN1DHODHMAOBMEN1LMNA | |
| SCHEMBL14679208 | 0.86 | PTPN1 (0.78) | PTPN1DHODHMAOBMEN1LMNA | |
| Kanzonol C SCHEMBL7185292 | 0.84 | PTPN1 (1.00) | PTPN1DHODHMAOBMEN1LMNA | |
| Kanzonol C SCHEMBL7179065 | 0.84 | PTPN1 (1.00) | PTPN1DHODHMAOBMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | claimed |
| EP-1623704-A1 | THERAPEUTIC AGENT | TAKARA BIO INC. (JP) | 2006-02-08 | — | — | EP | claimed |
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | disclosed |
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | disclosed |
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | disclosed |
| EP-1623704-A1 | THERAPEUTIC AGENT | TAKARA BIO INC. (JP) | 2006-02-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070092551-A1 | Therapeutic agent | FABP4, GPR119, IAPP | PTPN1 1950/4885DHODH 3351/4885MAOB 4382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.