Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032885 | 0.83 | ELANE (0.43) | TLR8TLR7POLBELANE | |
| SCHEMBL191231 | 0.75 | PRMT5 (0.44) | TP53TLR8TLR7PRMT5HPGD | |
| SCHEMBL30413516 | 0.74 | PRMT5 (0.42) | TP53TLR8TLR7PRMT5HPGD | |
| SCHEMBL311681 | 0.74 | PRMT5 (0.42) | TP53TLR8TLR7PRMT5HPGD | |
| SCHEMBL311313 | 0.74 | MMP2 (0.38) | TP53PRMT5KDM4EALDH1A1POLB | |
| SCHEMBL6221678 | 0.73 | DPP4 (0.40) | HPGDKDM4EALDH1A1NPSR1POLB | |
| SCHEMBL5350911 | 0.71 | HTT (0.36) | PRMT5KDM4EALDH1A1NPSR1BRD4 | |
| SCHEMBL5336423 | 0.70 | KDM4E (0.35) | TLR8TLR7PRMT5KDM4EALDH1A1 | |
| SCHEMBL5264585 | 0.70 | PRMT5 (0.38) | TLR8TLR7PRMT5KDM4EALDH1A1 | |
| Water SCHEMBL5259730 | 0.69 | PRMT5 (0.37) | TLR8TLR7PRMT5KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845980-A2 | AQUEOUS GEL FORMULATIONS CONTAINING 1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C][1,5]NAPHTHYRIDIN-4-AMINE | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006084073-A2 | AQUEOUS GEL FORMULATIONS CONTAINING 1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C][1,5]NAPHTHYRIDIN-4-AMINE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-08-10 | — | — | WO | disclosed |