SCHEMBL5516652

SCHEMBL5516652

NS(=O)(=O)CN1CCOCC1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.45
CA12 O43570 2/20 0.42
CA7 P43166 2/20 0.42
CA14 Q9ULX7 1/20 0.42
CA2 P00918 6/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KEAP1 Q14145 1/20 0.41
HSD17B10 Q99714 2/20 0.40
CA1 P00915 2/20 0.40
CA9 Q16790 2/20 0.40
HRH3 Q9Y5N1 1/20 0.39
TSHR P16473 2/20 0.39
ALOX15 P16050 1/20 0.39
ANPEP P15144 1/20 0.38
USP2 O75604 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
GLA P06280 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7050916 0.82
SCHEMBL426048 0.77 MEN1 (0.51) KDM4ECA12CA7CA14CA2
SCHEMBL5518034 0.77
SCHEMBL28068382 0.77 CA1 (0.43) CA2CA1HRH3ANPEPUSP2
SCHEMBL778925 0.76 CA12 (0.42) KDM4ECA12CA7CA14SMN1; SMN2
SCHEMBL4021995 0.76 KDM4E (0.45) KDM4ECA12CA7CA14SMN1; SMN2
SCHEMBL2377137 0.76 CA12 (0.42) KDM4ECA12CA7CA14SMN1; SMN2
Hydrochloric Acid SCHEMBL1291175 0.76 MEN1 (0.50) KDM4ECA12CA7CA14CA2
Hydrochloric Acid SCHEMBL23249493 0.75 CA1 (0.36) CA2CA1HRH3
SCHEMBL18064889 0.75 CA1 (0.48) CA2CA1HRH3TSHRANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707094-B1 Process for preparing perfluoroalkanesulfonyl fluorides MINNESOTA MINING & MFG (US) 1998-07-22 EP claimed
EP-0707094-A1 Process for preparing perfluoroalkanesulfonyl fluorides MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-04-17 EP claimed
US-12478680-B2 Hydrogels with biodegradable crosslinking PROLYNX LLC (US) 2025-11-25 US disclosed
US-20230135347-A1 HYDROGELS WITH BIODEGRADABLE CROSSLINKING PROLYNX LLC (US) 2023-05-04 US disclosed
US-11454861-B2 Hydrogels with biodegradable crosslinking PROLYNX LLC (US) 2022-09-27 US disclosed
EP-3464253-A1 AUTOTAXIN INHIBITORS University of Tennessee Research Foundation (US) 2019-04-10 EP disclosed
WO-2017210527-A1 AUTOTAXIN INHIBITORS UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2017-12-07 WO disclosed
US-7250444-B2 Pyrrole-based HMG-CoA reductase inhibitors PFIZER INC. (US) 2007-07-31 US disclosed
US-20060287378-A1 Novel pyrroles and imidazoles WARNER-LAMBERT COMPANY LLC 2006-12-21 US disclosed
EP-1656132-A2 NOVEL PYRROLE-BASED HMG-COA REDUCTASE INHIBITORS Warner-Lambert Company LLC (US) 2006-05-17 EP disclosed
US-20050043364-A1 Novel pyrrole-based HMG-CoA reductase inhibitors KENNEDY ROBERT MICHAEL (US) 2005-02-24 US disclosed
WO-2005014539-A2 PYRROLE-BASED HMG-COA REDUCTASE INHIBITORS WARNER-LAMBERT COMPANY LLC (US) 2005-02-17 WO disclosed
EP-0707094-B1 Process for preparing perfluoroalkanesulfonyl fluorides MINNESOTA MINING & MFG (US) 1998-07-22 EP disclosed
EP-0707094-A1 Process for preparing perfluoroalkanesulfonyl fluorides MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-04-17 EP disclosed
US-5486271-A Process for preparing perfluoroalkanesulfonyl fluorides MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-01-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050043364-A1 Novel pyrrole-based HMG-CoA reductase inhibitors HMGCR, DHCR7, HSD17B12 KDM4E 1231/4885CA12 4620/4885CA7 4085/4885
US-20230135347-A1 HYDROGELS WITH BIODEGRADABLE CROSSLINKING IDUA, APEH, GUSB KDM4E 1047/4885CA12 914/4885CA7 323/4885
US-20060287378-A1 Novel pyrroles and imidazoles PPIP5K2, PPIE, PPOX KDM4E 813/4885CA12 4451/4885CA7 3295/4885
US-11454861-B2 Hydrogels with biodegradable crosslinking IDUA, APEH, GUSB KDM4E 1047/4885CA12 914/4885CA7 323/4885
US-12478680-B2 Hydrogels with biodegradable crosslinking IDUA, APEH, GUSB KDM4E 1047/4885CA12 914/4885CA7 323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.