Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5510969 | 0.84 | LMNA (0.53) | GAAHRH3ALDH1A1POLB | |
| SCHEMBL31403181 | 0.84 | GAA (0.51) | GAASMN1; SMN2ALDH1A1CHRM1TDP1 | |
| SCHEMBL5520234 | 0.82 | KMT2A (0.42) | GAASMN1; SMN2HRH3POLB | |
| SCHEMBL11922661 | 0.82 | GAA (0.53) | GAASMN1; SMN2ALDH1A1CHRM1TDP1 | |
| SCHEMBL5515906 | 0.81 | ALDH1A1 (0.50) | GAAALDH1A1KDM4E | |
| SCHEMBL2745873 | 0.80 | GAA (0.51) | GAASMN1; SMN2ALDH1A1CHRM1TDP1 | |
| SCHEMBL5514914 | 0.80 | HRH3 (0.40) | HRH3ALDH1A1CHRM1 | |
| SCHEMBL5516041 | 0.80 | SMN1; SMN2 (0.43) | GAASMN1; SMN2HRH3ALDH1A1POLB | |
| SCHEMBL16708787 | 0.79 | HRH3 (0.39) | SMN1; SMN2HRH3ALDH1A1TDP1POLB | |
| SCHEMBL5513382 | 0.79 | HPGD (0.61) | SMN1; SMN2HRH3ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |