SCHEMBL5516801

SCHEMBL5516801

O=C(O)C(Nc1ccc[nH]1)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 1/20 0.38
KDM4E B2RXH2 2/20 0.37
GAA P10253 2/20 0.37
MAPT P10636 2/20 0.37
TSHR P16473 1/20 0.35
LMNA P02545 2/20 0.34
MAPK1 P28482 1/20 0.34
ATM Q13315 1/20 0.34
DAO P14920 1/20 0.33
BLM P54132 1/20 0.33
KMT2A Q03164 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6673703 0.81 NAPRT (0.36) NAPRTKDM4EGAAMAPTTSHR
SCHEMBL6673702 0.81 NAPRT (0.36) NAPRTKDM4EGAAMAPTTSHR
SCHEMBL3236321 0.78 LMNA (0.41) KDM4EGAAMAPTTSHRLMNA
SCHEMBL29240435 0.78 MME (0.37) NAPRTKDM4EGAAMAPTTSHR
SCHEMBL27738649 0.74 MME (0.48)
SCHEMBL30574571 0.74 GRN (0.46) MAPTLMNAMAPK1
SCHEMBL11143388 0.74 NAALAD2 (0.46) GAATSHR
SCHEMBL5513167 0.73 TSHR (0.37) NAPRTKDM4EGAAMAPTTSHR
Thiophene SCHEMBL7492246 0.73 ALDH1A1 (0.34) NAPRTLMNA
SCHEMBL3081010 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed