Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673703 | 1.00 | NAPRT (0.36) | NAPRTADAMTS4KDM4EGAAMAPT | |
| Thiophene SCHEMBL7492246 | 0.91 | ALDH1A1 (0.34) | NAPRTADAMTS4LMNA | |
| SCHEMBL3236321 | 0.82 | LMNA (0.41) | ADAMTS4KDM4EGAAMAPTTSHR | |
| SCHEMBL5516801 | 0.81 | NAPRT (0.38) | NAPRTKDM4EGAAMAPTTSHR | |
| SCHEMBL30574571 | 0.78 | GRN (0.46) | MAPTHTTLMNA | |
| SCHEMBL11542936 | 0.78 | — | — | |
| SCHEMBL18642528 | 0.77 | NAPRT (0.44) | NAPRTKDM4EGAAMAPTMEN1 | |
| SCHEMBL8003798 | 0.76 | — | — | |
| SCHEMBL29240435 | 0.75 | MME (0.37) | NAPRTKDM4EGAAMAPTTSHR | |
| SCHEMBL21603824 | 0.72 | TP53 (0.46) | KDM4EGAAMAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196608-B1 | NUCLEOSIDE-5'-OLIGOPHOSPHATES TAGGED WITH POSITIVELY-CHARGED POLYMERS, NANOPORES INCORPORATING NEGATIVE CHARGES, AND METHODS AND SYSTEMS USING THE SAME | HOFFMANN LA ROCHE (CH) | 2024-10-23 | — | — | EP | claimed |
| CN-118271335-A | Accurate positioning method for abasic site in genomic DNA | 北京大学 | 2024-07-02 | — | — | CN | claimed |
| CN-112566895-A | Cleavable linkers for peptide synthesis | 豪夫迈·罗氏有限公司 | 2021-03-26 | — | — | CN | claimed |
| EP-0394853-A1 | Dipeptide-derivatives with enzym-inhibiting activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-31 | — | — | EP | claimed |
| CN-118271335-A | Accurate positioning method for abasic site in genomic DNA | 北京大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-118271335-A | Accurate positioning method for abasic site in genomic DNA | 北京大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-112566895-B | Cleavable linkers for peptide synthesis | 豪夫迈·罗氏有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-113166203-A | Anti-erythropoietin receptor peptides | EPO医药株式会社 | 2021-07-23 | — | — | CN | disclosed |
| EP-1165509-B1 | METHOD OF PRODUCING 3,4-DIHYDROPROLINES AND 3,4-DEHYDROPIPERIDINES | ABBOTT GMBH & CO KG (DE) | 2004-10-06 | — | — | EP | disclosed |
| US-6579971-B1 | Derivatives by reacting with a strong base and compound of given formula; hydrolysis; useful intermediates for the synthesis of dyes, pesticides or drugs (thrombin inhibitors) | BASF AKTIENGESELLSCHAFT (DE) | 2003-06-17 | — | — | US | disclosed |
| EP-1165509-A1 | METHOD OF PRODUCING 3,4-DIHYDROPROLINES AND 3,4-DEHYDROPIPERIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058284-A1 | METHOD OF PRODUCING 3,4-DIHYDROPROLINES AND 3,4-DEHYDROPIPERIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-05 | — | — | WO | disclosed |