Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 3/20 | 0.42 |
| ▸ | CTRC | Q99895 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | PEPD | P12955 | 1/20 | 0.38 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5514975 | 0.91 | PIN1 (0.43) | ITGB3ITGA2BPIN1CMA1CTRC | |
| SCHEMBL5520395 | 0.84 | DPP8 (0.44) | ITGB3ITGA2BPIN1CMA1CTRC | |
| SCHEMBL5206182 | 0.81 | PIN1 (0.47) | PIN1PEPDXPNPEP1 | |
| SCHEMBL5203233 | 0.80 | PIN1 (0.54) | PIN1CMA1HDAC8PEPDXPNPEP1 | |
| SCHEMBL5205944 | 0.79 | PIN1 (0.53) | PIN1HDAC1HDAC8PEPDXPNPEP1 | |
| SCHEMBL5203122 | 0.79 | PIN1 (0.53) | PIN1HDAC1HDAC8PEPDXPNPEP1 | |
| SCHEMBL5206049 | 0.77 | PIN1 (0.57) | PIN1CMA1HDAC8PEPDXPNPEP1 | |
| SCHEMBL8479981 | 0.74 | CMA1 (0.42) | ITGB3ITGA2BCMA1CTRCHDAC1 | |
| SCHEMBL8478910 | 0.74 | CMA1 (0.42) | ITGB3ITGA2BCMA1CTRCHDAC1 | |
| SCHEMBL8461423 | 0.73 | CTSK (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070093492-A1 | Pyrrolidine derivatives | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2007-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093492-A1 | Pyrrolidine derivatives | DPP4, DPP7, DPP3 | ITGB3 4706/4885ITGA2B 4696/4885PIN1 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.