SCHEMBL5205944

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5203122	1.00	PIN1 (0.53)	PIN1CFDCTSSCTSKHDAC8
	SCHEMBL5203233	0.89	PIN1 (0.54)	PIN1CFDCTSSCTSKHDAC8
	SCHEMBL5206963	0.88	HDAC8 (0.45)	PIN1CFDCTSSCTSKHDAC8
	SCHEMBL5206049	0.86	PIN1 (0.57)	PIN1CFDCTSKHDAC8PEPD
	SCHEMBL3598521	0.82	CTSK (0.46)	CTSSCTSKHDAC8HDAC3HDAC4
	SCHEMBL5202988	0.82	DPP4 (0.59)	CTSSCTSKDPP4
	SCHEMBL5201959	0.82	DPP4 (0.59)	CTSSCTSKDPP4
	SCHEMBL5206182	0.81	PIN1 (0.47)	PIN1PEPDXPNPEP1
	SCHEMBL5203085	0.81	HDAC8 (0.51)	CTSSCTSKHDAC8HDAC3HDAC4
	SCHEMBL5696170	0.81	POLB (0.48)	CTSSCTSKHDAC8KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.