Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6018459 | 0.79 | NAPRT (0.61) | NAPRTHSD17B10NPC1RAB9AMAPT | |
| SCHEMBL15661401 | 0.79 | MAPT (0.53) | NAPRTHSD17B10NPC1RAB9AMAPT | |
| SCHEMBL5176170 | 0.77 | SMN1; SMN2 (0.50) | NAPRTHSD17B10NPC1RAB9AMAPT | |
| SCHEMBL10204717 | 0.77 | SMN1; SMN2 (0.50) | NAPRTHSD17B10NPC1RAB9AMAPT | |
| SCHEMBL219147 | 0.76 | KDM4E (0.66) | NAPRTHSD17B10NPC1RAB9AMAPT | |
| SCHEMBL5152326 | 0.75 | MTNR1A (0.56) | MAPTKMT2ASMN1; SMN2GAAKDM4E | |
| SCHEMBL15650174 | 0.75 | GAA (0.51) | NAPRTHSD17B10MAPTKMT2APOLB | |
| SCHEMBL11133832 | 0.75 | SMN1; SMN2 (0.48) | NAPRTHSD17B10NPC1RAB9AMAPT | |
| SCHEMBL5043930 | 0.75 | LMNA (0.48) | NAPRTHSD17B10NPC1RAB9AMAPT | |
| SCHEMBL6206428 | 0.75 | MAPT (0.56) | NAPRTHSD17B10NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848463-A2 | METHOD OF CONJUGATING AMINOTHIOL CONTAINING MOLECULES TO VEHICLES | Amgen Inc. (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006079099-A2 | METHOD OF CONJUGATING AMINOTHIOL CONTAINING MOLECULES TO A POLYMER | AMGEN INC. (US) | 2006-07-27 | — | — | WO | disclosed |