Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.37 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.37 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.37 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.37 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.37 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.37 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.37 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.37 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5520120 | 0.89 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2GAAALDH1A1MAPT | |
| SCHEMBL11922965 | 0.85 | LMNA (0.50) | HSD17B10LMNASMN1; SMN2GAANPSR1 | |
| SCHEMBL2744883 | 0.83 | LMNA (0.48) | HSD17B10LMNASMN1; SMN2GAANPSR1 | |
| SCHEMBL5516041 | 0.81 | SMN1; SMN2 (0.43) | HSD17B10LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL23466442 | 0.80 | HPGD (0.55) | LMNAKMT2A | |
| SCHEMBL5520234 | 0.80 | KMT2A (0.42) | HSD17B10LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL14683847 | 0.77 | HPGD (0.51) | HSD17B10LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL5512019 | 0.76 | STS (0.42) | HSD17B10LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5510969 | 0.76 | LMNA (0.53) | HSD17B10LMNAGAAHRH3ALDH1A1 | |
| SCHEMBL5516154 | 0.75 | STS (0.41) | HSD17B10LMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |