Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 10/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5516154 | 0.87 | STS (0.41) | STSMEN1KMT2ASMN1; SMN2HRH3 | |
| SCHEMBL5543694 | 0.86 | KMT2A (0.38) | STSMEN1KMT2ASMN1; SMN2HRH3 | |
| SCHEMBL5536873 | 0.85 | CNR1 (0.43) | STSCNR1CNR2MEN1KMT2A | |
| SCHEMBL5516041 | 0.82 | SMN1; SMN2 (0.43) | MEN1KMT2ASMN1; SMN2HRH3GAA | |
| SCHEMBL5520234 | 0.81 | KMT2A (0.42) | MEN1KMT2ASMN1; SMN2HRH3GAA | |
| SCHEMBL5540191 | 0.79 | CNR1 (0.39) | CNR1CNR2SMN1; SMN2HRH3EPHX2 | |
| SCHEMBL28974350 | 0.79 | STS (0.62) | STSKMT2APTPN2PTPN1PTPN6 | |
| SCHEMBL5510969 | 0.77 | LMNA (0.53) | HRH3GAAHSD17B10LMNA | |
| SCHEMBL16892272 | 0.77 | REV1 (0.43) | STSMEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL5517841 | 0.76 | HSD17B10 (0.49) | MEN1KMT2ASMN1; SMN2HRH3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |