Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | F13A1 | P00488 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | CA6 | P23280 | 2/20 | 0.54 |
| ▸ | CA5A | P35218 | 2/20 | 0.54 |
| ▸ | THPO | P40225 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.54 |
| ▸ | CASP2 | P42575 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522951 | 0.94 | ALOX15 (0.56) | ALOX15CA12F13A1CA2CYP1A2 | |
| SCHEMBL7518052 | 0.90 | TDP1 (0.52) | ALOX15CA12F13A1CA2CYP1A2 | |
| SCHEMBL9678656 | 0.90 | TDP1 (0.52) | ALOX15CA12F13A1CA2CYP1A2 | |
| SCHEMBL427900 | 0.89 | TDP1 (0.59) | ALOX15CA12F13A1CA2CYP1A2 | |
| SCHEMBL322792 | 0.89 | ALOX15 (0.54) | ALOX15CA12F13A1CA2CYP1A2 | |
| Hydrochloric Acid SCHEMBL6114403 | 0.88 | UBE2N (0.58) | ALOX15CA12F13A1CA2CYP1A2 | |
| SCHEMBL322920 | 0.88 | PAOX (0.53) | ALOX15CA12F13A1CA2CYP1A2 | |
| Hydrochloric Acid SCHEMBL28341342 | 0.88 | UBE2N (0.58) | ALOX15CA12F13A1CA2CYP1A2 | |
| SCHEMBL322999 | 0.88 | PAOX (0.53) | ALOX15CA12F13A1CA2CYP1A2 | |
| SCHEMBL323710 | 0.87 | TDP1 (0.61) | ALOX15CA12F13A1CA2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867633-A1 | Polyamine analogues as therapeutic and diagnostic agents | MediQuest Therapeutics, Inc. (US) | 2007-12-19 | — | — | EP | disclosed |
| EP-1001927-A2 | NOVEL POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS | ORIDIGM CORPORATION (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999003823-A2 | NOVEL POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS | ORIDIGM CORPORATION (US) | 1999-01-28 | — | — | WO | disclosed |