SCHEMBL5518548

SCHEMBL5518548

CNc1c(F)ccc2c(N)c(F)ccc12

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5511625 0.87 ADRA2A (0.31)
SCHEMBL5514278 0.82 KDM4E (0.32) KDM4EALDH1A1MAPT
SCHEMBL5508706 0.81
SCHEMBL5506924 0.79 ALDH1A1 (0.33) ALDH1A1MAPT
SCHEMBL5522881 0.79 ALDH1A1 (0.48) KDM4EALDH1A1MAPT
SCHEMBL5511694 0.75 ADRA2A (0.33)
SCHEMBL5511699 0.74 TSHR (0.38)
SCHEMBL5513036 0.73 IDO1 (0.33) ALDH1A1
SCHEMBL5508271 0.72 CRHBP (0.31) ALDH1A1MAPT
SCHEMBL5511146 0.72 IDO1 (0.41) KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208559-B2 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2007-04-24 US disclosed
US-20060135712-A1 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2006-06-22 US disclosed