Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1637217 | 0.80 | RAPGEF4 (0.46) | RAPGEF4TSHRKCNH2 | |
| SCHEMBL2541480 | 0.80 | RAPGEF4 (0.48) | RAPGEF4ALDH1A1 | |
| SCHEMBL5516191 | 0.78 | HDAC1 (0.41) | RAPGEF4TSHRKCNH2ALDH1A1 | |
| SCHEMBL5522888 | 0.78 | RAPGEF4 (0.46) | RAPGEF4TSHRALDH1A1 | |
| SCHEMBL25082732 | 0.76 | KCNH2 (0.34) | RAPGEF4TSHRKCNH2 | |
| SCHEMBL5513090 | 0.76 | RAPGEF4 (0.39) | RAPGEF4 | |
| SCHEMBL5517876 | 0.76 | MEP1B (0.37) | ALDH1A1TP53CYP3A4THRBHPGD | |
| SCHEMBL21482204 | 0.76 | TAAR1 (0.39) | ALDH1A1TP53CYP3A4THRBHPGD | |
| SCHEMBL5515615 | 0.76 | HDAC1 (0.40) | RAPGEF4TSHRKCNH2 | |
| SCHEMBL5510318 | 0.76 | TSHR (0.32) | RAPGEF4TSHRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022246086-A1 | ANTIBODY DRUG CONJUGATES USING MATES TECHNOLOGY FOR DELIVERING CYTOTOXIC AGENTS | BIOHAVEN THERAPEUTICS LTD. (US) | 2022-11-24 | — | — | WO | disclosed |
| US-7208559-B2 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2007-04-24 | — | — | US | disclosed |
| US-20060135712-A1 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2006-06-22 | — | — | US | disclosed |