SCHEMBL551928

SCHEMBL551928

CCC(CC)(C(=O)Cl)C(=O)Cl

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
ALDH1A1 P00352 5/20 0.36
TP53 P04637 1/20 0.35
TDP1 Q9NUW8 3/20 0.33
FFAR3 O14843 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15468819 0.85 ALDH1A1 (0.38) TSHRALDH1A1TP53TDP1
SCHEMBL1590219 0.85 ALDH1A1 (0.33) TSHRALDH1A1TP53FFAR3
SCHEMBL7170151 0.83 TSHR (0.38) TSHRALDH1A1TP53TDP1
SCHEMBL11733392 0.81 DGAT1 (0.34) TSHRALDH1A1
Pyridine SCHEMBL6245724 0.79 TSHR (0.38) TSHRALDH1A1TDP1
SCHEMBL11102231 0.79 ALDH1A1 (0.42) TSHRALDH1A1TP53
SCHEMBL20241522 0.75 DGAT1 (0.31) ALDH1A1
SCHEMBL2821206 0.75 CA1 (0.33)
SCHEMBL809272 0.75 TSHR (0.41) TSHRALDH1A1TP53TDP1FFAR3
SCHEMBL627727 0.73 TSHR (0.38) TSHRALDH1A1TP53TDP1FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119857380-A Gas separation membrane based on metal organic cage and preparation method and application thereof 天津大学 2025-04-22 CN claimed
US-20250109218-A1 METHOD FOR PREPARING CATALYST COMPONENT FOR POLYMERIZATION OF POLYOLEFIN WITHOUT THE USE OF INTERNAL ELECTRON DONORS FORMOSA PLASTICS CORP USA (US) 2025-04-03 US claimed
CN-117717902-B Preparation method and application of covalent organic framework nanofiltration membrane 天津大学 2024-07-26 CN claimed
CN-117717902-A Preparation method and application of covalent organic framework nanofiltration membrane 天津大学 2024-03-19 CN claimed
EP-1527128-B1 FUNCTIONALIZED ELASTOMER NANOCOMPOSITE EXXONMOBIL CHEM PATENTS INC (US) 2015-07-01 EP claimed
US-20130022569-A1 HYDROGELS NIH - DEITR 2013-01-24 US claimed
JP-4733978-B2 2011-07-27 JP claimed
US-20050277723-A1 Functionalized elastomer nanocomposite EXXONMOBIL CHEMICAL PATENTS INC. 2005-12-15 US claimed
JP-2005532448-A 2005-10-27 JP claimed
EP-1527128-A1 FUNCTIONALIZED ELASTOMER NANOCOMPOSITE ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2005-05-04 EP claimed
WO-2004005387-A1 FUNCTIONALIZED ELASTOMER NANOCOMPOSITE EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-15 WO claimed
US-6410741-B1 INSECTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-25 US claimed
WO-2000071542-A1 IMPROVED SYNTHESIS OF A TETRAAMIDO MACROCYCLE LIGAND THE CLOROX COMPANY (US) 2000-11-30 WO claimed
US-6127536-A Synthesis of a tetraamido macrocycle ligand THE CLOROX COMPANY (US) 2000-10-03 US claimed
WO-2026103814-A1 IRREVERSIBLE FAP INHIBITOR AND USE THEREOF 南京科络思生物科技有限公司 2026-05-21 WO disclosed
US-12583887-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-03-24 US disclosed
US-12559521-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-02-24 US disclosed
US-4182892-A CHEMICAL INTERMEDIATES FOR ACYLATION OF PEPTIDES OR PENAM-RING OR CEPHAM-RING CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) 1980-01-08 US disclosed
US-3976681-A DIURETIC, SALURETIC, URICOSURIC MERCK & CO., INC. (US) 1976-08-24 US disclosed
US-3966966-A DIURETICS MERCK & CO., INC. (US) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559521-B2 PSMA imaging agents KLK3, PSMA1, PSMA6 TSHR 744/4885ALDH1A1 2393/4885TP53 1870/4885
US-20130022569-A1 HYDROGELS PUF60, EPAS1, EGLN3 TSHR 4604/4885ALDH1A1 742/4885TP53 1421/4885
US-12583887-B2 PSMA imaging agents KLK3, PSMA3, PSMA1 TSHR 1304/4885ALDH1A1 2109/4885TP53 1553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.