Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL551928 | 0.85 | TSHR (0.38) | ALDH1A1TSHRTP53FFAR3 | |
| SCHEMBL51201 | 0.82 | FFAR3 (0.41) | ALDH1A1TSHRTP53FFAR3GRM2 | |
| Carbon Tetrachloride SCHEMBL10421671 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TSHRTP53FFAR3GRM2 | |
| SCHEMBL4382923 | 0.79 | FFAR3 (0.39) | ALDH1A1TSHRTP53FFAR3GRM2 | |
| Hydrochloric Acid SCHEMBL8053454 | 0.79 | FFAR3 (0.39) | ALDH1A1TSHRTP53FFAR3GRM2 | |
| SCHEMBL3673385 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TSHRTP53FFAR3GRM2 | |
| SCHEMBL28746064 | 0.79 | FFAR3 (0.39) | ALDH1A1TSHRTP53FFAR3GRM2 | |
| SCHEMBL104624 | 0.79 | FFAR3 (0.39) | ALDH1A1TSHRTP53FFAR3GRM2 | |
| SCHEMBL9489101 | 0.79 | FFAR3 (0.39) | ALDH1A1TSHRTP53FFAR3GRM2 | |
| SCHEMBL17818653 | 0.79 | FFAR3 (0.39) | ALDH1A1TSHRTP53FFAR3GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6219987-A | — | — | None | — | — | JP | disclosed |
| US-9944967-B2 | Methods for the site-selective introduction of halogen into natural products | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-17 | — | — | US | disclosed |
| US-20160201095-A1 | METHODS FOR THE SITE-SELECTIVE INTRODUCTION OF HALOGEN INTO NATURAL PRODUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-07-14 | — | — | US | disclosed |
| WO-2015026944-A1 | METHODS FOR THE SITE-SELECTIVE INTRODUCTION OF HALOGEN INTO NATURAL PRODUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-02-26 | — | — | WO | disclosed |
| US-20130078218-A1 | HEPATITIS C THERAPIES | BIOCRYST PHARMACEUTICALS, INC. | 2013-03-28 | — | — | US | disclosed |
| EP-2537520-A1 | Hepatics C therapies | Biocryst Pharmaceuticals, Inc. (US) | 2012-12-26 | — | — | EP | disclosed |
| US-8252833-B2 | Benzo (f) isoindol-2-ylphenyl acetic acid derivatives as EP4 receptor agonists | GLAXO GROUP LIMITED (GB) | 2012-08-28 | — | — | US | disclosed |
| EP-1979317-B1 | BENZOISOINDOLE DERIVATIVES FOR THE TREATMENT OF PAIN | GLAXO GROUP LTD (GB) | 2012-08-22 | — | — | EP | disclosed |
| EP-1979316-B1 | BENZO (F) ISOINDOL-2-YLPHENYL ACETIC ACID DERIVATIVES AS EP4 RECEPTOR AGONISTS | GLAXO GROUP LTD (GB) | 2012-07-11 | — | — | EP | disclosed |
| US-8207213-B2 | Benzoisoindole derivatives for the treatment of pain | GLAXO GROUP LIMITED (GB) | 2012-06-26 | — | — | US | disclosed |
| US-5194446-A | Antiarthritic agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-03-16 | — | — | US | disclosed |
| US-5025031-A | Aryl and aryloxyalkyl sulfamate esters useful as anticonvulsants | A. H. ROBINS CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |
| EP-0034951-B1 | PHOTOGRAPHIC EMULSIONS AND ELEMENTS CONTAINING BLOCKED 5-PYRAZOLONE MAGENTA DYE-FORMING COUPLERS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-02-05 | — | — | EP | disclosed |
| US-4545810-A | Herbicidal and plant growth regulant diphenylpyridazinones | SDS BIOTECH CORPORATION (US) | 1985-10-08 | — | — | US | disclosed |
| WO-1982000402-A1 | HERBICIDAL AND PLANT GROWTH REGULANT DIPHENYLPYRIDAZINONES | DIAMOND SHAMROCK CORP (US) | 1982-02-18 | — | — | WO | disclosed |
| EP-0046069-A1 | Herbicidal and plant growth regulant diphenylpyridazinones | DIAMOND SHAMROCK CORPORATION (US) | 1982-02-17 | — | — | EP | disclosed |
| US-4310618-A | Silver halide photographic material and process utilizing blocked dye-forming couplers | EASTMAN KODAK COMPANY (US) | 1982-01-12 | — | — | US | disclosed |
| US-4283472-A | HAVING GOOD STORAGE STABILITY AND REACTIVITY | EASTMAN KODAK COMPANY (US) | 1981-08-11 | — | — | US | disclosed |
| US-4168371-A | Process for making lignin gels in bead form | WESTVACO CORPORATION (US) | 1979-09-18 | — | — | US | disclosed |
| US-4131573-A | CROSSLINKING | WESTVACO CORPORATION (US) | 1978-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130078218-A1 | HEPATITIS C THERAPIES | HAVCR2, FABP1, LIPC | ALDH1A1 435/4885TSHR 4341/4885TP53 1221/4885 |
| US-20160201095-A1 | METHODS FOR THE SITE-SELECTIVE INTRODUCTION OF HALOGEN INTO NATURAL PRODUCTS | HDHD5, COASY, DHPS | ALDH1A1 649/4885TSHR 3104/4885TP53 1748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.