SCHEMBL5519639

SCHEMBL5519639

O=C(O)CNC(=O)CNC(=O)CCl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TSHR P16473 1/20 0.43
EGLN1 Q9GZT9 2/20 0.38
ITGB1 P05556 1/20 0.37
ITGA5 P08648 1/20 0.37
MAPT P10636 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
LMNA P02545 1/20 0.37
PTGS2 P35354 1/20 0.37
FAAH O00519 5/20 0.36
MME P08473 1/20 0.35
ACE P12821 1/20 0.35
CPA1 P15085 1/20 0.35
ACE2 Q9BYF1 1/20 0.35
PTPN1 P18031 1/20 0.35
CTH P32929 1/20 0.34
MEN1 O00255 2/20 0.34
APEX1 P27695 2/20 0.34
KMT2A Q03164 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4786380 1.00 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2TSHREGLN1ITGB1
SCHEMBL1965772 0.95
SCHEMBL10067714 0.79 EGLN1 (0.41) ALDH1A1EGLN1ITGB1ITGA5MAPT
SCHEMBL10630632 0.78 TSHR (0.41) ALDH1A1SMN1; SMN2TSHREGLN1ITGB1
SCHEMBL10711707 0.78 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2TSHRLMNASLC6A5
SCHEMBL13336065 0.77 CA1 (0.45) ALDH1A1EGLN1ITGB1ITGA5MAPT
SCHEMBL4804241 0.77 ALDH1A1 (0.39) ALDH1A1EGLN1ITGB1ITGA5MAPT
SCHEMBL3376460 0.77 ALDH1A1 (0.39) ALDH1A1EGLN1ITGB1ITGA5MAPT
SCHEMBL4804250 0.77 PTPN1 (0.40) ALDH1A1EGLN1ITGB1ITGA5MAPT
SCHEMBL2807522 0.75 EGLN1 (0.46) ALDH1A1EGLN1ITGB1ITGA5MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118727156-A Universal monocrystalline silicon texturing additive, texturing solution containing same, preparation method and application thereof 浙江奥首材料科技有限公司 2024-10-01 CN claimed
CN-118727156-A Universal monocrystalline silicon texturing additive, texturing solution containing same, preparation method and application thereof 浙江奥首材料科技有限公司 2024-10-01 CN disclosed
CN-110419477-B Culture method of macrobrachium rosenbergii seedlings 苏州市毛氏阳澄湖水产发展有限公司 2021-09-17 CN disclosed
US-20070042030-A1 Preparation for the application of agents in mini-droplets IDEA AG (DE) 2007-02-22 US disclosed
EP-0475160-B2 Preparation for drug application in minute droplet form IDEA AG (DE) 2004-07-14 EP disclosed
US-20020048598-A1 INTERNALLY SUPPORTED LIPID VESICLE SYSTEMS MALIK NAVID (GB) 2002-04-25 US disclosed
WO-2001041827-A1 INTERNALLY SUPPORTED BIOMIMETIC MATERIALS AND COATINGS MALIK NAVID (GB) 2001-06-14 WO disclosed
US-6165500-A Preparation for the application of agents in mini-droplets IDEA AG (DE) 2000-12-26 US disclosed
EP-0998267-A1 INTERNALLY SUPPORTED LIPID VESICLE SYSTEMS Malik, Navid (GB) 2000-05-10 EP disclosed
WO-1998056353-A1 INTERNALLY SUPPORTED LIPID VESICLE SYSTEMS MALIK NAVID (GB) 1998-12-17 WO disclosed
EP-0475160-B1 Preparation for drug application in minute droplet form IDEA AG (DE) 1996-02-14 EP disclosed
EP-0475160-A1 Preparation for drug application in minute droplet form Cevc, Gregor, Prof. Dr. (DE) 1992-03-18 EP disclosed
WO-1992003122-A1 PREPARATION FOR APPLICATION OF ACTIVE SUBSTANCES IN THE FORM OF MINIMUM-SIZED DROPLETS CEVC GREGOR (DE) 1992-03-05 WO disclosed
US-5092885-A Antitumor agents, wouond healing agents, promoters of cell adhesion to prostheses THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1992-03-03 US disclosed
US-5066716-A Synthesis of chloroacetyl and bromoacetyl modified peptides for the preparation of synthetic peptide polymers, conjugated peptides, and cyclic peptides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1991-11-19 US disclosed
US-4786684-A SOLID PHASE SYNTHESIS THE MOUNT SINAI SCHOOL OF MEDICINE OF THE CITY UNIVERSITY OF NEW YORK (US) 1988-11-22 US disclosed
WO-1988001173-A1 BENZYLTHIOETHER-LINKED SOLID SUPPORT-BOUND THIOL COMPOUNDS AND METHOD FOR PEPTIDE SYNTHESIS THE MOUNT SINAI SCHOOL OF MEDICINE (US) 1988-02-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020048598-A1 INTERNALLY SUPPORTED LIPID VESICLE SYSTEMS STARD3, CHMP4B, EXOSC10 ALDH1A1 3732/4885SMN1; SMN2 3896/4885TSHR 3247/4885
US-20070042030-A1 Preparation for the application of agents in mini-droplets FABP4, NPC1L1, LIPA ALDH1A1 3560/4885SMN1; SMN2 4016/4885TSHR 2808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.