Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 1/20 | 0.48 |
| ▸ | MARS1 | P56192 | 3/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 13/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5522335 | 0.85 | MARS1 (0.47) | RPA1MARS1MALT1BCL2MDM2 | |
| SCHEMBL5522098 | 0.83 | MARS1 (0.64) | RPA1MARS1BCL2MDM2MCL1 | |
| SCHEMBL5524647 | 0.83 | KMT2A (0.52) | RPA1MARS1BCL2MDM2MCL1 | |
| SCHEMBL5524365 | 0.81 | RPA1 (0.44) | RPA1MARS1MALT1BCL2MDM2 | |
| SCHEMBL5531835 | 0.79 | CNR1 (0.51) | RPA1MARS1MALT1KDM1ASLC16A3 | |
| SCHEMBL5519940 | 0.76 | RPA1 (0.38) | RPA1MALT1KDM1A | |
| SCHEMBL16876862 | 0.73 | CA9 (0.55) | RPA1KDM1A | |
| SCHEMBL16876774 | 0.73 | RPA1 (0.60) | RPA1MARS1BCL2MDM2MCL1 | |
| SCHEMBL4929781 | 0.72 | KMT2A (0.51) | BCL2MDM2MCL1 | |
| SCHEMBL5521163 | 0.72 | OXTR (0.45) | RPA1MALT1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1698626-A1 | AMIDOPYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | PTGER1, PTGS1, PTGER2 | RPA1 1661/4885MARS1 2982/4885MALT1 3117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.