Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 3/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.43 |
| ▸ | RPA1 | P27694 | 4/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.41 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5519928 | 0.85 | RPA1 (0.48) | MARS1MALT1RPA1MDM2MCL1 | |
| SCHEMBL5524365 | 0.85 | RPA1 (0.44) | MARS1MALT1RPA1MDM2MCL1 | |
| Hydrochloric Acid SCHEMBL5151848 | 0.81 | MALT1 (0.43) | MALT1RPA1MDM2MCL1BCL2 | |
| SCHEMBL6207899 | 0.81 | CHRNA7 (0.55) | MARS1MALT1RPA1MDM2MCL1 | |
| SCHEMBL5523089 | 0.80 | CNR1 (0.53) | MARS1MALT1SLC16A3SLC16A1CYP2A6 | |
| Hydrochloric Acid SCHEMBL5148814 | 0.80 | CHRNA7 (0.54) | MARS1MALT1RPA1MDM2MCL1 | |
| SCHEMBL5522089 | 0.74 | MALT1 (0.35) | MALT1RPA1 | |
| SCHEMBL14504508 | 0.74 | MALT1 (0.42) | MALT1RPA1MDM2MCL1BCL2 | |
| SCHEMBL14504509 | 0.73 | CHRNA7 (0.53) | MARS1MALT1RPA1MDM2MCL1 | |
| SCHEMBL14504623 | 0.71 | MALT1 (0.43) | MARS1MALT1RPA1MDM2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1698626-A1 | AMIDOPYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | PTGER1, PTGS1, PTGER2 | MARS1 2982/4885MALT1 3117/4885RPA1 1661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.