Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 4/20 | 0.45 |
| ▸ | S100B | P04271 | 2/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28717217 | 0.86 | MAPT (0.55) | MAPTKMT2AALDH1A1HTR6MEN1 | |
| Hydrochloric Acid SCHEMBL27660780 | 0.83 | MAPT (0.51) | MAPTKMT2AALDH1A1CYP1A2MEN1 | |
| SCHEMBL25042438 | 0.80 | HTR6 (0.42) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL25039682 | 0.79 | MAPT (0.55) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL21485052 | 0.77 | S100B (0.59) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL2933216 | 0.77 | LMNA (0.51) | MAPTKMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL14826478 | 0.76 | MAPT (0.58) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL13105505 | 0.76 | MAPT (0.46) | MAPTKMT2AALDH1A1HTTKDM4E | |
| SCHEMBL19998610 | 0.76 | HPGD (0.47) | MAPTKMT2AALDH1A1HPGDS100B | |
| SCHEMBL24140816 | 0.75 | S100B (0.51) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213339-A1 | Quinolone Carboxylic Acid Derivatives for Treatment of Hyperproliferative Conditions | BAYER PHARMACEUTICALS CORPORATION (US) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213339-A1 | Quinolone Carboxylic Acid Derivatives for Treatment of Hyperproliferative Conditions | TP53, RB1, HRAS | MAPT 4397/4885KMT2A 2389/4885ALDH1A1 272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.