Sugi Predict

Sugi Predict / Compounds / SCHEMBL552005

SCHEMBL552005

SCHEMBL552005

CSCC(C)(C)NC(=O)c1c(I)cccc1C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ KMT2A Q03164 4/20 0.34
▸ MEN1 O00255 2/20 0.34
▸ ALOX15 P16050 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ PPARG P37231 1/20 0.33
▸ NR1H4 Q96RI1 1/20 0.33
▸ PKM P14618 1/20 0.32
▸ KDM4E B2RXH2 2/20 0.32
▸ NPC1 O15118 2/20 0.32
▸ RAB9A P51151 2/20 0.32
▸ CASP3 P42574 1/20 0.32
▸ SENP8 Q96LD8 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ SENP7 Q9BQF6 1/20 0.32
▸ SENP6 Q9GZR1 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.31
▸ GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29459709 1.00 POLB (0.35) POLBNPSR1L3MBTL1KMT2AMEN1
SCHEMBL552006 0.90 NPSR1 (0.38) POLBNPSR1L3MBTL1KMT2AMEN1
SCHEMBL551442 0.84 FABP4 (0.37) POLBNPSR1L3MBTL1KMT2AMEN1
SCHEMBL550487 0.84 ALB (0.40) POLBNPSR1L3MBTL1KMT2AMEN1
SCHEMBL551671 0.84 PBRM1 (0.42) POLBKMT2AMEN1ALDH1A1HPGD
SCHEMBL2963051 0.84 SMN1; SMN2 (0.36) POLBL3MBTL1KMT2AMEN1ALOX15
SCHEMBL550320 0.80 KMT2A (0.50) POLBNPSR1L3MBTL1KMT2AMEN1
SCHEMBL10211763 0.80 MAPT (0.51) L3MBTL1KMT2AMEN1PKMKDM4E
Iodide SCHEMBL29459706 0.79 KMT2A (0.49) POLBNPSR1L3MBTL1KMT2AMEN1
SCHEMBL28621890 0.79 L3MBTL1 (0.35) POLBNPSR1L3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109020934-B Preparation method of intermediate containing halogenated benzene ring side chain flubendiamide structure 绍兴贝斯美化工股份有限公司 2022-03-08 — — CN claimed
CN-109574892-B Method for preparing 3-iodine-N- (1, 1-dimethyl-2-methylthioethyl) o-carbamoylbenzoic acid by microchannel reaction 常州沃腾化工科技有限公司 2020-11-17 — — CN claimed
CN-102807541-A Preparation method of 3-iodo-N-(1,1-dimethyl-2-methylmercaptoethyl) isophthalamide HUNAN RES INST CHEMICAL IND 2012-12-05 — — CN claimed
CN-109020934-B Preparation method of intermediate containing halogenated benzene ring side chain flubendiamide structure 绍兴贝斯美化工股份有限公司 2022-03-08 — — CN disclosed
CN-109020934-B Preparation method of intermediate containing halogenated benzene ring side chain flubendiamide structure 绍兴贝斯美化工股份有限公司 2022-03-08 — — CN disclosed
CN-109180543-B Preparation method of pesticide intermediate containing halogenated benzene ring bisamide side chain structure 绍兴贝斯美化工股份有限公司 2021-05-25 — — CN disclosed
CN-109574892-B Method for preparing 3-iodine-N- (1, 1-dimethyl-2-methylthioethyl) o-carbamoylbenzoic acid by microchannel reaction 常州沃腾化工科技有限公司 2020-11-17 — — CN disclosed
CN-104402785-A Novel bisamides derivative and preparation method and application thereof UNIV NANKAI 2015-03-11 — — CN disclosed
CN-102807541-A Preparation method of 3-iodo-N-(1,1-dimethyl-2-methylmercaptoethyl) isophthalamide HUNAN RES INST CHEMICAL IND 2012-12-05 — — CN disclosed
CN-102807541-A Preparation method of 3-iodo-N-(1,1-dimethyl-2-methylmercaptoethyl) isophthalamide HUNAN RES INST CHEMICAL IND 2012-12-05 — — CN disclosed
CN-101198589-B N-benzanilides with insecticidal activity BAYER CROPSCIENCE AG 2012-07-18 — — CN disclosed
CN-101198589-A N-benzanilides with insecticidal activity BAYER CROPSCIENCE AG (DE) 2008-06-11 — — CN disclosed
EP-1893567-A1 BENZANILIDES WITH INSECTICIDAL ACTIVITY Bayer CropScience AG (DE) 2008-03-05 — — EP disclosed
US-20070299085-A1 N1-((Pyrazol-1-Ymethyl)-2-Methylphenyl)-Phatalamide Derivatives And Related Compounds Insecticides BAYER CROPSCIENCE AG (DE) 2007-12-27 — — US disclosed
US-20070299085-A1 N1-((Pyrazol-1-Ymethyl)-2-Methylphenyl)-Phatalamide Derivatives And Related Compounds Insecticides BAYER CROPSCIENCE AG (DE) 2007-12-27 — — US disclosed
US-20070299085-A1 N1-((Pyrazol-1-Ymethyl)-2-Methylphenyl)-Phatalamide Derivatives And Related Compounds Insecticides BAYER CROPSCIENCE AG (DE) 2007-12-27 — — US disclosed
CN-1930129-A N1- ((pyrazol-1-ylmethyl) -2-methylphenyl) -phthalamide derivative and related compound insecticide BAYER CROPSCIENCE AG (DE) 2007-03-14 — — CN disclosed
WO-2006133823-A1 BENZANILIDES WITH INSECTICIDAL ACTIVITY BAYER CROPSCIENCE AG (DE) 2006-12-21 — — WO disclosed
EP-1727804-A1 N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES Bayer CropScience Aktiengesellschaft (DE) 2006-12-06 — — EP disclosed
WO-2005095351-A1 N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES BAYER CROPSCIENCE AG (DE) 2005-10-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070299085-A1 N1-((Pyrazol-1-Ymethyl)-2-Methylphenyl)-Phatalamide Derivatives And Related Compounds Insecticides CHRM1, KCNH1, DDT POLB 4401/4885NPSR1 1470/4885L3MBTL1 518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.