Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 14/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | INSR | P06213 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ATP4A | P20648 | 1/20 | 0.43 |
| ▸ | ATP4B | P51164 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5520870 | 1.00 | APP (0.61) | APPPTGS1STSINSRMAOA | |
| SCHEMBL11136663 | 0.89 | INSR (0.51) | APPINSRATP4AATP4BMEN1 | |
| SCHEMBL11136666 | 0.89 | INSR (0.51) | APPINSRATP4AATP4BMEN1 | |
| SCHEMBL6531891 | 0.84 | APP (0.61) | APPINSRATP4AATP4BMEN1 | |
| SCHEMBL30446042 | 0.84 | APP (0.61) | APPINSRATP4AATP4BMEN1 | |
| SCHEMBL29788323 | 0.82 | APP (0.56) | APPSTSATP4AATP4BMEN1 | |
| SCHEMBL29397958 | 0.81 | MEN1 (0.59) | APPINSRATP4AATP4BMEN1 | |
| SCHEMBL476616 | 0.81 | MEN1 (0.59) | APPINSRATP4AATP4BMEN1 | |
| SCHEMBL476617 | 0.81 | MEN1 (0.59) | APPINSRATP4AATP4BMEN1 | |
| SCHEMBL6492845 | 0.79 | INSR (0.47) | APPINSRATP4AATP4BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2944626-B1 | MR IMAGING DIAGNOSTIC AGENT FOR INTRACTABLE NEUROLOGICAL DISEASE | UNIV SHIGA MEDICAL SCIENCE (JP) | 2018-10-10 | — | — | EP | disclosed |
| US-20150352232-A1 | MR IMAGING DIAGNOSTIC AGENT FOR INTRACTABLE NEUROLOGICAL DISEASE | SHIGA UNIVERSITY OF MEDICAL SCIENCE (JP) | 2015-12-10 | — | — | US | disclosed |
| EP-2944626-A1 | MR IMAGING DIAGNOSTIC AGENT FOR INTRACTABLE NEUROLOGICAL DISEASE | Shiga University Of Medical Science (JP) | 2015-11-18 | — | — | EP | disclosed |
| US-20070031328-A1 | Radiolabeled-pegylation of ligands for use as imaging agents | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150352232-A1 | MR IMAGING DIAGNOSTIC AGENT FOR INTRACTABLE NEUROLOGICAL DISEASE | TARDBP, FUS, SNCA | APP 19/4885PTGS1 4566/4885STS 4823/4885 |
| US-20070031328-A1 | Radiolabeled-pegylation of ligands for use as imaging agents | EGFR, LANCL1, FLT1 | APP 4458/4885PTGS1 1652/4885STS 3068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.