Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | CTSL | P07711 | 1/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5521050 | 1.00 | ALDH1A1 (0.74) | ALDH1A1CTSLATMMETTL3 | |
| SCHEMBL5522779 | 0.83 | CTSL (0.70) | ALDH1A1CTSLATMMETTL3 | |
| SCHEMBL5519818 | 0.83 | CTSL (0.70) | ALDH1A1CTSLATMMETTL3 | |
| SCHEMBL13954747 | 0.83 | CTSL (0.70) | ALDH1A1CTSLATMMETTL3 | |
| SCHEMBL5522782 | 0.83 | CTSL (0.70) | ALDH1A1CTSLATMMETTL3 | |
| SCHEMBL940737 | 0.83 | CTSL (0.70) | ALDH1A1CTSLATMMETTL3 | |
| SCHEMBL941204 | 0.83 | CTSL (0.70) | ALDH1A1CTSLATMMETTL3 | |
| SCHEMBL17527524 | 0.83 | CTSL (0.70) | ALDH1A1CTSLATMMETTL3 | |
| Phenyl(Methyl)Thiosemicarbazone SCHEMBL27879446 | 0.82 | METTL3 (0.90) | ALDH1A1ATMMETTL3 | |
| SCHEMBL8443303 | 0.81 | CTSL (0.68) | CTSLATMMETTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197495-A1 | ANTI-PARASITIC COMPOUNDS AND METHODS OF THEIR USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197495-A1 | ANTI-PARASITIC COMPOUNDS AND METHODS OF THEIR USE | CYP51A1, TUBA3C, PIGO | ALDH1A1 860/4885CTSL 5/4885ATM 4843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.