SCHEMBL5521676

SCHEMBL5521676

O=C(O)C(CCCOc1ccc[nH]1)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.42
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
TSHR P16473 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPK1 P28482 1/20 0.35
PPARG P37231 4/20 0.33
PPARA Q07869 3/20 0.33
NAPRT Q6XQN6 1/20 0.33
GAA P10253 2/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
PTGES O14684 1/20 0.32
ALOX5 P09917 1/20 0.32
PPARD Q03181 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5515854 0.92 PPARG (0.37) TDP1TSHRL3MBTL1MAPK1PPARG
SCHEMBL5510987 0.81 TSHR (0.37) TDP1MEN1KMT2ATSHRL3MBTL1
SCHEMBL5509637 0.79 TSHR (0.47) TSHRALDH1A1MAPK1PPARASMN1; SMN2
SCHEMBL5512352 0.78 PPARA (0.47) TSHRALDH1A1PPARAMAPT
SCHEMBL5515513 0.77 TSHR (0.49) TSHRL3MBTL1PPARANAPRTGAA
SCHEMBL6670235 0.73 ALDH1A1 (0.33) ALDH1A1GAAKDM4E
SCHEMBL5523873 0.73 TDP1 (0.70) TDP1MEN1KMT2ATSHRL3MBTL1
SCHEMBL5511532 0.73 ALOX15 (0.50) TDP1MEN1KMT2ATSHRL3MBTL1
SCHEMBL10364117 0.72
SCHEMBL4276902 0.71 GAA (0.47) TDP1TSHRL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed