SCHEMBL5510987

SCHEMBL5510987

O=C(O)C(COc1ccc[nH]1)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
NAPRT Q6XQN6 1/20 0.36
MAPT P10636 3/20 0.35
GAA P10253 2/20 0.35
KDM4E B2RXH2 1/20 0.35
RAB9A P51151 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34
POLB P06746 2/20 0.33
SRR Q9GZT4 2/20 0.33
RECQL P46063 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NPC1 O15118 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KDM4C Q9H3R0 1/20 0.32
DAO P14920 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5515854 0.82 PPARG (0.37) TSHRNAPRTMAPTGAAKDM4E
SCHEMBL5521676 0.81 TDP1 (0.42) TSHRNAPRTMAPTGAAKDM4E
SCHEMBL5511532 0.77 ALOX15 (0.50) TSHRMAPTGAAKDM4ERAB9A
SCHEMBL5515513 0.74 TSHR (0.49) TSHRNAPRTGAAPPARAL3MBTL1
SCHEMBL5513657 0.73 LDHA (0.41) TSHRNAPRTMAPTGAAKDM4E
SCHEMBL5509637 0.73 TSHR (0.47) TSHRMAPTSMN1; SMN2PPARA
SCHEMBL3258515 0.72 KDM4E (0.43) TSHRMAPTGAAKDM4ERAB9A
SCHEMBL5512352 0.71 PPARA (0.47) TSHRMAPTPPARA
SCHEMBL10895229 0.71
SCHEMBL15546096 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed