Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | BCL9 | O00512 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22137002 | 0.90 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL26226843 | 0.90 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL16284648 | 0.90 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2032096 | 0.88 | HTR2A (0.50) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5983721 | 0.86 | MGLL (0.48) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL25911506 | 0.83 | MAPT (0.53) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7341887 | 0.79 | MAPT (0.64) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6449604 | 0.79 | MGLL (0.52) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL19668455 | 0.79 | MAPT (0.64) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5764186 | 0.78 | HTR2A (0.61) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199105-B2 | Lincomycin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS, INC. (US) | 2007-04-03 | — | — | US | disclosed |
| US-20040230046-A1 | Lincomycin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040230046-A1 | Lincomycin derivatives possessing antibacterial activity | NRDC, NISCH, CLSPN | ALDH1A1 2737/4885MAPT 4332/4885SMN1; SMN2 3897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.