Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | BCL9 | O00512 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5521767 | 0.88 | ALDH1A1 (0.57) | HTR2AMGLLMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2390983 | 0.87 | MAPT (0.55) | HTR2AMGLLMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29401387 | 0.87 | MAPT (0.55) | HTR2AMGLLMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2390989 | 0.87 | MAPT (0.55) | HTR2AMGLLMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL24058871 | 0.82 | MGLL (0.52) | HTR2AMGLLMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL19871006 | 0.82 | MGLL (0.52) | HTR2AMGLLMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL25911506 | 0.82 | MAPT (0.53) | HTR2AMGLLMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL28845985 | 0.81 | PPARA (0.56) | HTR2AMGLLMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL28845986 | 0.81 | PPARA (0.56) | HTR2AMGLLMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL28845978 | 0.81 | ALDH1A1 (0.49) | HTR2AMGLLMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110150980-A1 | CGRP ANALOG | VASOGENIX PHARMACEUTICALS, INC. (US) | 2011-06-23 | — | — | US | disclosed |