Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.60 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.58 |
| ▸ | CASP2 | P42575 | 1/20 | 0.53 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | PPARD | Q03181 | 3/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | TLR2 | O60603 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19400289 | 1.00 | MEN1 (0.71) | MEN1KMT2AADRA1APRMT1EPHX2 | |
| SCHEMBL20009655 | 1.00 | MEN1 (0.71) | MEN1KMT2AADRA1APRMT1EPHX2 | |
| SCHEMBL19400283 | 1.00 | MEN1 (0.71) | MEN1KMT2AADRA1APRMT1EPHX2 | |
| SCHEMBL9265462 | 1.00 | MEN1 (0.71) | MEN1KMT2AADRA1APRMT1EPHX2 | |
| SCHEMBL45902 | 0.98 | MEN1 (0.74) | MEN1KMT2AADRA1APRMT1EPHX2 | |
| SCHEMBL1912627 | 0.91 | MEN1 (0.70) | MEN1KMT2AADRA1APRMT1EPHX2 | |
| SCHEMBL11758762 | 0.87 | MEN1 (0.94) | MEN1KMT2ACASP2ALDH1A1 | |
| SCHEMBL21765846 | 0.87 | MEN1 (0.94) | MEN1KMT2ACASP2ALDH1A1 | |
| SCHEMBL9259257 | 0.87 | MEN1 (0.94) | MEN1KMT2ACASP2ALDH1A1 | |
| SCHEMBL9262199 | 0.86 | CASP2 (0.74) | MEN1KMT2AADRA1APRMT1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070027310-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2007-02-01 | — | — | US | claimed |
| US-20040132981-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2004-07-08 | — | — | US | claimed |
| EP-1289561-A2 | LIGAND CONJUGATES AND METHODS FOR PREPARING SAME | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2003-03-12 | — | — | EP | claimed |
| US-20010051348-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2001-12-13 | — | — | US | claimed |
| WO-2001054731-A2 | LIGAND CONJUGATES AND METHODS FOR PREPARING SAME | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2001-08-02 | — | — | WO | claimed |
| US-4007266-A | Pharmaceutical composition containing vitamin B12, process of making the same and method of treatment | CHOAY S.A. (FR) | 1977-02-08 | — | — | US | claimed |
| US-20170049906-A1 | TRANSLOCATION OF NON-NATURAL CHEMICAL ENTITIES THROUGH ANTHRAX PROTECTIVE ANTIGEN PORE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-02-23 | — | — | US | disclosed |
| US-20070027310-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2007-02-01 | — | — | US | disclosed |
| US-7153977-B2 | Ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2006-12-26 | — | — | US | disclosed |
| US-20040132981-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2004-07-08 | — | — | US | disclosed |
| EP-1289561-A2 | LIGAND CONJUGATES AND METHODS FOR PREPARING SAME | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2003-03-12 | — | — | EP | disclosed |
| US-20010051348-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2001-12-13 | — | — | US | disclosed |
| WO-2001054731-A2 | LIGAND CONJUGATES AND METHODS FOR PREPARING SAME | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2001-08-02 | — | — | WO | disclosed |
| US-5310905-A | Conversion of nylon 6 and/or nylon 6,6 to monomers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-05-10 | — | — | US | disclosed |
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |
| US-4243678-A | GASTROINTESTINAL DISORDERS, LIVER DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-01-06 | — | — | US | disclosed |
| US-4007266-A | Pharmaceutical composition containing vitamin B12, process of making the same and method of treatment | CHOAY S.A. (FR) | 1977-02-08 | — | — | US | disclosed |
| US-3908018-A | Therapeutical and cosmetic composition including N-propionyl-epsilon-amino-caproic acid | CHOAY SA | 1975-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010051348-A1 | Novel ligands and methods for preparing same | ADGRF1, ADGRE5, TACR2 | MEN1 3183/4885KMT2A 4370/4885ADRA1A 442/4885 |
| US-20070027310-A1 | Novel ligands and methods for preparing same | ADGRF1, ADGRE5, TACR2 | MEN1 3183/4885KMT2A 4370/4885ADRA1A 442/4885 |
| US-20040132981-A1 | Novel ligands and methods for preparing same | ADGRF1, ADGRE5, TACR2 | MEN1 3183/4885KMT2A 4370/4885ADRA1A 442/4885 |
| US-20170049906-A1 | TRANSLOCATION OF NON-NATURAL CHEMICAL ENTITIES THROUGH ANTHRAX PROTECTIVE ANTIGEN PORE | ANTXR2, SLC47A2, SLC47A1 | MEN1 2937/4885KMT2A 3925/4885ADRA1A 4384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.