Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.57 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.55 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20009655 | 0.98 | MEN1 (0.71) | MEN1KMT2AADRA1APRMT1EPHX2 | |
| SCHEMBL19400289 | 0.98 | MEN1 (0.71) | MEN1KMT2AADRA1APRMT1EPHX2 | |
| SCHEMBL9265462 | 0.98 | MEN1 (0.71) | MEN1KMT2AADRA1APRMT1EPHX2 | |
| SCHEMBL19400283 | 0.98 | MEN1 (0.71) | MEN1KMT2AADRA1APRMT1EPHX2 | |
| SCHEMBL5522638 | 0.98 | MEN1 (0.71) | MEN1KMT2AADRA1APRMT1EPHX2 | |
| SCHEMBL1912627 | 0.93 | MEN1 (0.70) | MEN1KMT2AADRA1APRMT1EPHX2 | |
| SCHEMBL17229157 | 0.86 | MEN1 (1.00) | MEN1KMT2ACASP2KDM4E | |
| SCHEMBL9830305 | 0.85 | CASP2 (0.70) | MEN1KMT2AADRA1APRMT1EPHX2 | |
| SCHEMBL1709332 | 0.84 | MEN1 (0.61) | MEN1KMT2AADRA1AEPHX2PLA2G2A | |
| SCHEMBL31317660 | 0.84 | PRMT1 (0.67) | MEN1KMT2AADRA1APRMT1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150540-A1 | HYDROXAMIC ACID MACROCYCLIC AGENTS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. (US) | 2023-08-10 | — | — | WO | disclosed |
| US-10239878-B2 | Macrocyclic ligands with pendant chelating moieties and complexes thereof | LUMIPHORE, INC. (US) | 2019-03-26 | — | — | US | disclosed |
| US-20180194766-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2018-07-12 | — | — | US | disclosed |
| US-9522980-B2 | Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2016-12-20 | — | — | US | disclosed |
| WO-2011140318-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND USES OF THE SAME | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2011-11-10 | — | — | WO | disclosed |
| US-20110275734-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE, INC. | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194766-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | TFRC, CLTC, SLC39A3 | MEN1 390/4885KMT2A 3990/4885ADRA1A 4485/4885 |
| US-10239878-B2 | Macrocyclic ligands with pendant chelating moieties and complexes thereof | TFRC, CLTC, SLC39A3 | MEN1 390/4885KMT2A 3990/4885ADRA1A 4485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.