Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5524542 | 0.80 | ALOX5 (0.46) | KMT2AMAPTTDP1MEN1PARP10 | |
| SCHEMBL2755026 | 0.80 | KMT2A (0.68) | KMT2AMAPTTDP1MEN1PARP10 | |
| SCHEMBL20429162 | 0.75 | TAAR1 (0.49) | KMT2AMAPTTDP1MEN1PARP10 | |
| Hydrochloric Acid SCHEMBL11194414 | 0.75 | HTT (0.53) | KMT2AALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11036696 | 0.75 | BCHE (0.59) | MAPTTDP1L3MBTL1LMNA | |
| SCHEMBL11418028 | 0.74 | KMT2A (0.57) | KMT2AMAPTTDP1MEN1PARP10 | |
| SCHEMBL12649365 | 0.73 | KMT2A (0.59) | KMT2AMAPTTDP1MEN1PARP10 | |
| SCHEMBL17383940 | 0.73 | KMT2A (0.59) | KMT2AMAPTTDP1MEN1PARP10 | |
| SCHEMBL23111290 | 0.73 | KMT2A (0.47) | KMT2AMAPTTDP1MEN1PARP10 | |
| SCHEMBL1785471 | 0.73 | KMT2A (0.69) | KMT2AMAPTTDP1MEN1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205425-B2 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | CHISSO CORPORATION (JP) | 2007-04-17 | — | — | US | disclosed |
| US-20070060656-A1 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | SHIBASAKI MASAKATSU | 2007-03-15 | — | — | US | disclosed |
| US-20050148801-A1 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | JNC CORPORATION (JP) | 2005-07-07 | — | — | US | disclosed |
| EP-0947498-B1 | OPTICALLY ACTIVE NITRO ALCOHOL DERIVATIVES, OPTICALLY ACTIVE AMINO ALCOHOL DERIVATIVES, AND PROCESS FOR PREPARING THE SAME | CHISSO CORP (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6632955-B1 | Optically active 1-substituted phenyl-2-nitro alcohol derivatives which are useful pharmaceutical intermediates. Enantiomotphs active 1-substituted phenyl-2-nitro alcohol derivatives. From these nitro alcohol such as albutramin and | CHISSO CORPORATION (JP) | 2003-10-14 | — | — | US | disclosed |
| US-20020193447-A1 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | JNC CORPORATION (JP) | 2002-12-19 | — | — | US | disclosed |
| EP-0947498-A1 | OPTICALLY ACTIVE NITRO ALCOHOL DERIVATIVES, OPTICALLY ACTIVE AMINO ALCOHOL DERIVATES, AND PROCESS FOR PREPARING THE SAME | CHISSO CORPORATION (JP) | 1999-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148801-A1 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | ADH1A, ALDH7A1, ADRB1 | KMT2A 3532/4885MAPT 2856/4885TDP1 2914/4885 |
| US-20070060656-A1 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | ADH1A, ALDH7A1, ADRB1 | KMT2A 3532/4885MAPT 2856/4885TDP1 2914/4885 |
| US-20020193447-A1 | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof | ADH1A, ALDH7A1, SARM1 | KMT2A 3443/4885MAPT 2862/4885TDP1 2853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.