Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 10/20 | 0.67 |
| ▸ | AAK1 | Q2M2I8 | 10/20 | 0.55 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5524963 | 1.00 | IMPDH2 (0.67) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL5531753 | 0.99 | IMPDH2 (0.66) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL5531750 | 0.99 | IMPDH2 (0.66) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL1473510 | 0.84 | IMPDH2 (0.67) | IMPDH2AAK1 | |
| SCHEMBL1473512 | 0.84 | IMPDH2 (0.67) | IMPDH2AAK1 | |
| SCHEMBL1474348 | 0.83 | IMPDH2 (0.66) | IMPDH2AAK1 | |
| SCHEMBL1474349 | 0.83 | IMPDH2 (0.66) | IMPDH2AAK1 | |
| SCHEMBL6170243 | 0.82 | IMPDH2 (0.73) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL5524837 | 0.82 | IMPDH2 (0.64) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL6171745 | 0.77 | IMPDH2 (0.66) | IMPDH2AAK1IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765336-A2 | ANGIOGENESIS INHIBITORS | THE JOHNS-HOPKINS UNIVERSITY (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006004795-A2 | ANGIOGENESIS INHIBITORS | THE JOHNS HOPKINS UNIVERSITY (US) | 2006-01-12 | — | — | WO | disclosed |