Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 6/20 | 0.35 |
| ▸ | DRD1 | P21728 | 4/20 | 0.35 |
| ▸ | DRD5 | P21918 | 4/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3768100 | 0.94 | MEN1 (0.38) | DRD2MEN1KMT2AATMHTR1A | |
| SCHEMBL3761431 | 0.91 | DRD2 (0.44) | DRD2MEN1KMT2ATSHRKDM2B | |
| SCHEMBL5511812 | 0.85 | DRD2 (0.38) | DRD2MEN1KMT2AATMHTR1A | |
| SCHEMBL5510711 | 0.84 | DRD2 (0.47) | DRD2HTR1ADRD1DRD5DRD4 | |
| SCHEMBL2783246 | 0.83 | DRD2 (0.37) | DRD2MEN1KMT2AHTR1ADRD1 | |
| SCHEMBL3767620 | 0.83 | DRD2 (0.39) | DRD2MEN1KMT2AHTR1ADRD1 | |
| SCHEMBL5517963 | 0.82 | DRD2 (0.36) | DRD2DRD1DRD5DRD4DRD3 | |
| SCHEMBL3765947 | 0.82 | DRD2 (0.57) | DRD2DRD1DRD5DRD4DRD3 | |
| SCHEMBL3772533 | 0.82 | SIGMAR1 (0.39) | DRD2MEN1KMT2AHTR1ADRD1 | |
| SCHEMBL5503809 | 0.82 | RBP4 (0.46) | DRD2TSHRDRD1DRD3ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768958-A1 | NEW DISUBSTITUTED PHENYLPIPERIDINES AS MODULATORS OF DOPAMINE AND SEROTONIN NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2007-04-04 | — | — | EP | disclosed |
| WO-2005121088-A1 | NEW DISUBSTITUTED PHENYLPIPERIDINES AS MODULATORS OF DOPAMINE AND SEROTONIN NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2005-12-22 | — | — | WO | disclosed |