Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 15/20 | 0.40 |
| ▸ | BCKDK | O14874 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5528337 | 0.88 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13494106 | 0.84 | CYP1A2 (0.43) | P2RX7BCKDKNPC1CYP1A2CYP2C19 | |
| SCHEMBL5520108 | 0.83 | POLB (0.39) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10266407 | 0.82 | P2RX7 (0.39) | P2RX7BCKDKNPC1CYP1A2CYP2C19 | |
| SCHEMBL5524260 | 0.80 | PPARA (0.40) | RAB9ASMN1; SMN2 | |
| SCHEMBL5521998 | 0.79 | HCAR2 (0.46) | TRPV1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5524256 | 0.78 | RAB9A (0.43) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5520215 | 0.76 | ALDH1A1 (0.41) | NPC1SMN1; SMN2 | |
| SCHEMBL5522175 | 0.75 | SMN1; SMN2 (0.41) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5522358 | 0.75 | RAB9A (0.51) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | P2RX7 2375/4885BCKDK 554/4885TRPV1 4123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.