Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.54 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.54 |
| ▸ | BRSK1 | Q8TDC3 | 2/20 | 0.54 |
| ▸ | SRPK1 | Q96SB4 | 2/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.54 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.54 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.54 |
| ▸ | SRC | P12931 | 2/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.54 |
| ▸ | PLK4 | O00444 | 1/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.54 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.54 |
| ▸ | RET | P07949 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
| ▸ | PRKACA | P17612 | 1/20 | 0.54 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12648993 | 0.82 | DHFR (0.55) | DHFRDCPSADORA2AKCNH2 | |
| SCHEMBL30482740 | 0.82 | ADORA2A (0.55) | MAP4K4DHFRADORA1DCPSADORA2A | |
| SCHEMBL1154898 | 0.82 | MAP4K4 (0.58) | MAP4K4DHFRADORA1DCPSADORA2A | |
| SCHEMBL30482722 | 0.78 | DHFR (0.45) | DHFRDCPSKCNH2 | |
| SCHEMBL19826965 | 0.78 | DHFR (0.54) | DHFRADORA1DCPSKCNH2 | |
| SCHEMBL30482718 | 0.77 | DHFR (0.56) | DHFRDCPSADORA2AKCNH2 | |
| SCHEMBL5525855 | 0.76 | SMN1; SMN2 (0.51) | DHFRADORA1DCPSADORA2AADORA2B | |
| SCHEMBL30482725 | 0.76 | DHFR (0.46) | DHFRDCPSADORA2AKCNH2 | |
| SCHEMBL27631513 | 0.75 | PIK3CG (0.59) | FLT3CSNK1DDYRK1ABRSK1SRPK1 | |
| SCHEMBL21497083 | 0.75 | DCPS (0.47) | DHFRDCPSKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142402-A1 | Kinase Inhibitors And Their Uses | RIGEL PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142402-A1 | Kinase Inhibitors And Their Uses | BTK, SYK, LYN | FLT3 19/4885CSNK1D 393/4885DYRK1A 311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.