Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5525210 | 0.88 | POLB (0.36) | ABL1RIN1POLBSMN1; SMN2P2RY6 | |
| SCHEMBL5531861 | 0.86 | P2RY6 (0.40) | ABL1RIN1POLBSMN1; SMN2P2RY6 | |
| SCHEMBL6932273 | 0.82 | POLB (0.44) | ABL1RIN1POLBP2RY6P2RY14 | |
| SCHEMBL12404747 | 0.80 | POLB (0.49) | ABL1RIN1POLBP2RY6P2RY14 | |
| SCHEMBL6365679 | 0.79 | POLB (0.45) | ABL1RIN1POLBP2RY6P2RY14 | |
| SCHEMBL7736293 | 0.78 | POLB (0.43) | ABL1RIN1POLBSMN1; SMN2P2RY6 | |
| SCHEMBL5523429 | 0.78 | P2RY6 (0.43) | ABL1RIN1POLBHPGDSMN1; SMN2 | |
| SCHEMBL6365808 | 0.77 | P2RY6 (0.47) | ABL1RIN1POLBP2RY6P2RY14 | |
| SCHEMBL13672352 | 0.77 | P2RY6 (0.47) | ABL1RIN1POLBP2RY6P2RY14 | |
| SCHEMBL13151571 | 0.77 | P2RY6 (0.47) | ABL1RIN1POLBP2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070172925-A1 | Ribonucleic acid compound and method of liquid-phase synthesis of oligonucleic acid compound | NIPPON SHINYAKU CO., LTD. (JP) | 2007-07-26 | — | — | US | disclosed |
| EP-1710249-A1 | RIBONUCLEIC ACID COMPOUND AND METHOD OF LIQUID-PHASE SYNTHESIS OF OLIGONUCLEIC ACID COMPOUND | Nippon Shinyaku Co., Ltd. (JP) | 2006-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070172925-A1 | Ribonucleic acid compound and method of liquid-phase synthesis of oligonucleic acid compound | RNASEH1, NSUN2, POLR2H | ABL1 3391/4885RIN1 2186/4885POLB 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.